PMID: 15238817Jul 9, 2004Paper

Effects of statin therapy on vascular dysfunction

Coronary Artery Disease
Masanori Aikawa

Abstract

Dyslipidemia and vascular inflammation play critical roles in the onset of acute coronary syndromes including myocardial infarction. Recent advances in cardiovascular medicine demonstrate that lipid-lowering therapy by 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) prevents acute coronary complications, probably by limiting inflammation in atheroma. Although a number of studies have suggested various effects of statins on vascular dysfunction independent of lipid lowering, the clinical benefits of such effects are not established as yet.

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Citations

Aug 13, 2013·Journal of Vascular Surgery·Min-Woong SohnWilliam B Pearce
Jan 17, 2014·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Uğur CanpolatSinan Aydoğdu
Mar 15, 2006·Current Opinion in Anaesthesiology·Olaf Schouten, Don Poldermans
Sep 15, 2020·Restorative Neurology and Neuroscience·Jiaying ZhuLi He

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