Effects of storage time on total protein and globulin concentrations in bovine fresh frozen plasma obtained for transfusion

TheScientificWorldJournal
D ProverbioR Perego

Abstract

To evaluate the effects of storage conditions on total protein (TP) and globulin fractions in fresh frozen bovine plasma units prepared and stored for transfusion, TP and globulin fractions were evaluated in fresh plasma and at 1 month and 6 and 12 months after blood collection in plasma stored at -20°C. Significant differences in concentrations were found in the median concentration of total protein (P=0.0336), between 0 months and 1 month (P=0.0108), 0 and 6 months (P=0.0023), and 0 and 12 months (P=0.0027), in mean concentration (g/dL) of albumin (P=0.0394), between 0 months and 1 month (P=0.0131), 0 and 6 months (P=0.0035), and 0 and 12 months (P=0.0038), and beta-2 fraction (P=0.0401), between 0 and 6 months (P=0.0401) and 0 and 12 months (P=0.0230). This study suggests that total gamma globulin concentration in bovine frozen plasma is stable for 12 months at -20°C. Total protein, ALB, and beta-2 fraction have significantly different concentrations (g/dL) when compared to prestorage. This study has shown IgG protein fraction stability in bovine fresh frozen plasma collected for transfusion; therefore, bovine fresh frozen plasma seems to be suitable for the treatment of hypogammaglobulinemia (failure of passive transfer) in...Continue Reading

References

May 1, 1979·Infection and Immunity·K C SatijaV K Sharma
Feb 1, 1989·Journal of Dairy Science·S K DeNiseD V Armstrong
May 1, 1988·Journal of Dairy Science·J D RobisonS K DeNise
Apr 30, 1998·Journal of Veterinary Internal Medicine·J W TylerC C Gay
Sep 13, 2006·Veterinary Clinical Pathology·Brice ReynoldsHervé Pierre Lefebvre
Jan 11, 2011·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Daniela AlberghinaGiuseppe Piccione
Jul 2, 2014·The Veterinary Clinics of North America. Food Animal Practice·Christie Balcomb, Derek Foster

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Methods Mentioned

BETA
blood collection
electrophoresis

Software Mentioned

XP Pro
MedCalc
Phoresis

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