Effects of sugars on leucine and lysine uptake by intestinal cells from rats fed sucrose and stock diets.

Proceedings of the Society for Experimental Biology and Medicine
S ReiserJ Hallfrisch

Abstract

The effect of various dietary sugars on the uptake of 1 mM leucine and 1 mM lysine by intestinal cells isolated from stock-fed and sucrose-fed rats was determined. Leucine uptake was activated by 10 mM fructose and inhibited by 10 mM glucose or 20 mM sucrose on both diets. The major dietary effect noted was a significant increase in the inhibition of leucine by glucose in the sucrose-fed rats. The uptake of lysine was minimally affected by the sugars irrespective of the diet fed. These results demonstrate an important dichotomy in the properties of glucose and fructose transport in the intestine and suggest that dietary fructose may increase the transport of certain amino acids.

Citations

Sep 8, 2007·European Journal of Nutrition·Dharam P ChaudharyDevi D Bansal
Jan 1, 1980·Journal of Neural Transmission·J M Cottet-EmardJ Bonnod
May 13, 2008·Journal of Animal Science·P R RegmiM Oba
Jan 1, 1980·Zeitschrift für Tierphysiologie, Tierernährung und Futtermittelkunde·V K Garg

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