Effects of supplementation of green tea extract on the milk performance of peripartal dairy cows and the expression of stress response genes in the liver

Journal of Animal Science and Biotechnology
Denise K GessnerKlaus Eder

Abstract

We hypothesised that supplementation of green tea extract (GTE) in dairy cows during the transition period can attenuate proinflammatory conditions and prevent endoplasmic reticulum (ER) stress in the liver of these cows. Thirty Holstein cows with an average parity of 3.06 (± 1.31, SD) were divided into a control group and a group that received a daily amount of 10 g of GTE from d 7 before the calving day and a daily amount of 20 g of GTE from the day of calving until d 7 of lactation. Cows supplemented with GTE did not show differences in energy intake or milk yield in weeks 2-7 of lactation. However, these cows had a lower milk fat concentration and a lower energy corrected milk yield than the control cows and showed a trend of improved energy balance. The relative mRNA concentrations of proinflammatory genes, genes involved in the acute phase reaction and antioxidant genes in the liver in weeks 1, 4 and 7 of lactation were not different between the two groups of cows. The concentrations of α-tocopherol and the Trolox equivalent antioxidant capacity in plasma were not different between the two groups. However, the group supplemented with GTE showed significant reductions of some genes of the unfolded protein response (UPR) in...Continue Reading

References

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Jul 28, 2016·Journal of Animal Physiology and Animal Nutrition·D K GessnerK Eder
Nov 15, 2018·Journal of Agricultural and Food Chemistry·Liwen WangShiming Li
Dec 27, 2018·Nutrients·Naghma Khan, Hasan Mukhtar

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Methods Mentioned

BETA
infrared
biopsies
enzyme-linked immunosorbent assay

Software Mentioned

Primer3
R core
lattice
lsmeans
multcomp
BLAST
Power
geNorm
nlme
predictmeans

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