PMID: 6113800Jan 1, 1981Paper

Effects of surgery on plasma amino acids levels

Annales de l'anesthésiologie française
G FrançoisM Blanc

Abstract

This study was aimed at comparing pre- and immediately postoperative plasma amino acids levels in ten patients undergoing moderately important surgery and anaesthetised using the same protocol. Amino acid levels were measured using and automatic analyser equipped with an ion exchanger column. Changes in total blood amino acid levels showed wide variations. It is difficult to assess the role played by possible changes in blood volume, and for this reason results are expressed as a percentage of total amino acid levels. Under such conditions, findings were as follows: - taurine and alamine rose significantly; - there was a significant fall in serine, citrulline, alpha- amino-butyric acid and isoleucine. The results of this study differed markedly from findings reported in the literature: the authors noted a fall in plasma amino acid levels both in relation to preoperative levels as well as in relation to "normal" levels in the literature. This could be related to haemodilution, this hypothesis being supported by the fall in total aminogram in eight of the ten patients of the group. The most notable fact in the variations seen in this study was the rise in plasma alamine levels which could be indicative of a fall in gluconeogenesi...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.