Effects of Surgical Methods and Tumor Location on Survival and Recurrence Patterns after Curative Resection in Patients with T2 Gallbladder Cancer

Gut and Liver
Woohyun JungSun-Whe Kim

Abstract

Extended cholecystectomy is generally recommended for patients with T2 gallbladder cancer. However, few studies have assessed the extent of resection relative to T2 gallbladder tumor location. This study analyzed the effects of surgical methods and tumor location on survival outcomes and tumor recurrence in patients with T2 gallbladder cancer. Clinicopathological characteristics, extent of resection, survival rates, and recurrence patterns were retrospectively analyzed in 88 patients with pathologically confirmed T2 gallbladder cancer. The 5-year disease-free survival rate was 65.0%. Multivariate analysis showed that lymph node metastasis was the only independent risk factor for poor 5-year disease-free survival rate. Survival outcomes were not associated with tumor location. Survival tended to be better in patients who underwent extended cholecystectomy than in those who underwent simple cholecystectomy. Recurrence rate was not affected by surgical method or tumor location. Systemic recurrence was more frequent than local recurrence without distant recurrence. Gallbladder bed recurrence and liver recurrence were relatively rare, occurring only in patients with liver side tumors. Extended cholecystectomy is the most appropriate...Continue Reading

References

Nov 1, 1992·Annals of Surgery·Y ShiraiH Watanabe
Apr 1, 1992·American Journal of Surgery·K Yamaguchi, M Tsuneyoshi
Jan 1, 1995·Cancer·M T Carriaga, D E Henson
May 3, 2001·Journal of the American College of Surgeons·K ChijiiwaM Tanaka
May 8, 2003·Annals of Surgical Oncology·Toshifumi WakaiKatsuyoshi Hatakeyama
Jul 1, 1962·Annals of Surgery·R B FAHIMD O FERRIS
Oct 19, 2005·Journal of Surgical Oncology·Ryoko SasakiKazuyoshi Saito
Feb 4, 2006·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Xabier de AretxabalaF Maluenda
Nov 15, 2006·Annals of Surgical Oncology·Jason M FosterBoris Kuvshinoff
May 18, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Masahiro KaiKazuhiro Kondo
Aug 9, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Chang Moo KangByong Ro Kim
Nov 17, 2007·American Journal of Surgery·Byron E WrightAnton J Bilchik
Feb 16, 2008·Journal of Hepato-biliary-pancreatic Surgery·Satoshi KondoUNKNOWN Japan Society of Clinical Oncology
May 2, 2009·Journal of the National Comprehensive Cancer Network : JNCCN·Al B BensonAndrew X Zhu
Dec 25, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Sae Byeol ChoiSang Yong Choi
Feb 17, 2010·Archives of Surgery·Jai Young ChoKyoung-Ho Lee
Sep 9, 2010·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Skye C MayoTimothy M Pawlik
Sep 25, 2012·World Journal of Gastroenterology : WJG·Yoshio ShiraiKatsuyoshi Hatakeyama
Aug 21, 2013·World Journal of Surgery·Dong Hyun KimWoo Jung Lee
Nov 5, 2014·Journal of Korean Medical Science·Seung Eun LeeUNKNOWN Korean Association of Hepato-Biliary and Pancreas Surgery

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Citations

Apr 15, 2020·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Yu-Chuan LiangJin-Yan Wang
Dec 2, 2019·World Journal of Surgical Oncology·Suguru MaruyamaDaisuke Ichikawa
Sep 7, 2017·Langenbeck's Archives of Surgery·Hiroshi KuraharaShoji Natsugoe
Jul 10, 2018·Journal of Korean Medical Science·Seung Eun LeeUNKNOWN Korean Pancreas Surgery Club
Mar 9, 2017·Scandinavian Journal of Gastroenterology·Malin Sternby EilardPer Sandström
Apr 25, 2018·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·Iago JustoLuis Carlos Jiménez-Romero
Feb 3, 2021·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Felipe B MaegawaIoannis T Konstantinidis
Dec 29, 2020·Journal of Surgical Oncology·Natasha LeighBenjamin J Golas

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Methods Mentioned

BETA
surgical resection
dissection

Software Mentioned

SPSS

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