Effects of synthetic craniofacial materials on cerebral microcirculation

The Journal of Craniofacial Surgery
C M BaroneA T Clapper

Abstract

Four groups were studied to look at effects of synthetic materials on the pial vasculature. Using Sprague-Dawley rats, an open pial window approach was used in which there was a control group, a hydroxyapatite cement group mixed with sodium phosphate, a methylmethacrylate slow-set, and a methylmethacrylate fast-set group. There were 10 animals with 20 vessels studied within each group. The permeability leakage outside the vessel was evaluated to determine the vascular albumin leakage, and the number of rolling and adherent leukocytes was studied within each group. It was seen that the control group was significantly different compared with the fast-set methylmethacrylate group during a 2-hour period in regard to the percentage leakage, as well as a number of rolling and adherent leukocytes. This is one of the first studies to demonstrate the effects of synthetic craniofacial materials on the underlying pial vasculature.

References

Jan 1, 1987·International Orthopaedics·R J SchultzS Krishnamurthy
Jan 1, 1995·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·S Toksvig-LarsenB Strömqvist
Feb 1, 1994·Acta Orthopaedica Scandinavica·J StürupJ S Jensen
Feb 8, 2000·The Journal of Burn Care & Rehabilitation·C M BaroneX F Yang
Apr 21, 2001·The Journal of Craniofacial Surgery·C M BaroneB W Beckert

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Citations

Feb 8, 2005·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Jan Michael KuemmerleBrigitte von Rechenberg
May 22, 2016·Materials Science & Engineering. C, Materials for Biological Applications·Basel A Khader, Mark R Towler
Dec 7, 2018·Journal of Biomaterials Science. Polymer Edition·Xiaoxia FanYonggang Yan

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