PMID: 2494392Jan 1, 1989Paper

Effects of tannins from different sources on airway epithelial and platelet function

Lung
M M Cloutier, M S Rohrbach

Abstract

The uniqueness of tannin isolated from aqueous extracts of cotton bracts (CBE) on the electrophysiological and ion transport properties of the canine tracheal epithelium and on 5-hydroxytryptamine (5-HT) release from platelets was investigated. The effect of CBE from Deltapine 41 cotton picked before (green, containing high-concentration, high-molecular-weight tannin) and after (brown, containing low-concentration, low-molecular-weight tannin) senescence and Darjeeling tea extracts and tannin isolated from Darjeeling tea were compared to the effects of Acala SJ-2 CBE and Acala SJ-2 tannin. Green Deltapine 41 CBE was similar to Acala SJ-2 CBE in decreasing short-circuit current (Isc) and net chloride secretion and in producing a dose-response release of 5-HT from platelets. Both Green and Brown Deltapine 41 CBE altered the paracellular pathway, but were less potent than Acala SJ-2 CBE. Brown Deltapine 41 CBE stimulated chloride transport in the airway epithelium and did not produce 5-HT release from human platelets. Darjeeling tea and tea tannin increased Isc and net chloride secretion and caused 5-HT release from platelets only at high concentrations. These studies demonstrate that all tannins are not alike; they suggest that m...Continue Reading

References

May 1, 1977·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·M G MarinJ A Nadel
Aug 1, 1976·The American Journal of Physiology·K G Orloff, D Michaeli
Jan 1, 1987·American Journal of Industrial Medicine·M M KawamotoL Bernstein
Sep 3, 1987·The New England Journal of Medicine·R M CastellanJ L Hankinson
Jan 1, 1974·Annals of the New York Academy of Sciences·M Hitchcock
Jun 1, 1969·Biochemical Pharmacology·F CarpenedoR Santi
Apr 1, 1971·British Journal of Industrial Medicine·G TaylorF Lucas
Feb 1, 1984·Chest·J H EdwardsH Bunny
Apr 1, 1981·Chest·M H Noweir
Apr 1, 1981·Chest·R M CastellanJ A Merchant

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Citations

Jan 1, 1994·American Journal of Industrial Medicine·M S Rohrbach
Oct 27, 2004·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·E DeharoG Bourdy
Dec 30, 1998·The Journal of Nutrition·E AndriambelosonR Andriantsitohaina

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