Effects of thalamic deep brain stimulation based on tremor type and diagnosis

Movement Disorders : Official Journal of the Movement Disorder Society
J P HubbleW C Koller

Abstract

It has been suggested that deep brain stimulation (DBS) is less effective in alleviating proximal than distal postural arm tremor reduction is said to be less in essential tremor (ET) than in Parkinson's disease (PD). We analyzed blinded rater's tremor scores and subjects' disability ratings at 3-month follow-up to examine the effects of DBS based on tremor type (rest, kinetic, distal postural, proximal postural) and diagnosis (ET, PD). An independent examiner provided tremor scores using randomized videotaped footage of 19 ET and 10 PD subjects at baseline and at follow-up with DBS "on." Subjects provided self-ratings of disability at baseline and at follow-up. Comparisons of baseline and follow-up tremor scores and disability ratings were made using the Mann-Whitney U and Wilcoxon rank sum W test; correlation analyses were performed using Spearman rank order correlation test. There were significant and essentially equal improvements in tremor scores of test, kinetic, distal postural, and proximal postural tremor at follow-up. Only one subject had no improvement in tremor. Tremor improved significantly and to the same extent in ET and PD subjects in each position except "at rest," which was most improved in PD (p = 0.0003). ET...Continue Reading

Citations

Apr 12, 2002·Movement Disorders : Official Journal of the Movement Disorder Society·Hagai Bergman, Günther Deuschl
Apr 12, 2002·Movement Disorders : Official Journal of the Movement Disorder Society·Pierre PollakAlim-Louis Benabid
Jun 27, 2008·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Selcuk PekerMemet Ozek
Jan 1, 2008·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Hong Yu, Joseph S Neimat
Dec 4, 2003·Parkinsonism & Related Disorders·J D PutzkeR J Uitti
Oct 19, 2000·Archives of Medical Research·A M Lozano
Mar 3, 1998·Journal of the American College of Surgeons·I A Awad
Apr 14, 2011·Nature Reviews. Neurology·Félix Bermejo-Pareja
Sep 1, 1999·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·J WeaverA Torres
Jun 24, 2004·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Paul T MartinelliBruce R Nelson
Jan 14, 1999·Journal of Neurology, Neurosurgery, and Psychiatry·X LiuJ F Stein
Aug 20, 2002·Journal of Neurology, Neurosurgery, and Psychiatry·J VesperUNKNOWN Kinetra Study Group
Jan 16, 2007·Journal of Neurosurgery·Rodrigo MercadoChristopher R Honey
Aug 29, 2014·Surgical Neurology International·Damián BenderskyClaudio Yampolsky
Nov 28, 2006·Computer Aided Surgery : Official Journal of the International Society for Computer Aided Surgery·Ting GuoTerry M Peters
Nov 23, 2013·Neurosurgery Clinics of North America·Rob DallapiazzaW Jeff Elias
Nov 24, 2004·Lancet Neurology·Benjamin L Walter, Jerrold L Vitek
Feb 24, 2004·Neurological Research·Joshua M RosenowAli R Rezai
Apr 29, 2004·Neurosurgery·Efstathios PapavassiliouPhilip A Starr
Mar 16, 2017·Stereotactic and Functional Neurosurgery·Lidia Cabañes-MartínezIgnacio Regidor Bailly-Bailliere
Jul 1, 2006·Movement Disorders : Official Journal of the Movement Disorder Society·Günther DeuschlValerie Voon
Mar 15, 2006·Stereotactic and Functional Neurosurgery·Daniel TarsyThorkild Norregaard
Sep 16, 2008·Neurosurgery·Ali R RezaiNicholas M Boulis
Jun 7, 2005·Journal of Speech, Language, and Hearing Research : JSLHR·Anna FarrellPeter Silburn
Mar 9, 2007·Journal of Neurophysiology·Jan RaethjenGünther Deuschl
May 3, 2019·Movement Disorders : Official Journal of the Movement Disorder Society·Joaquim J FerreiraUNKNOWN MDS Task Force on Tremor and the MDS Evidence Based Medicine Committee
Nov 5, 1998·Neurosurgery·P A StarrR A Bakay
Nov 25, 1998·Movement Disorders : Official Journal of the Movement Disorder Society·J D SpeelmanD A Bosch
Nov 30, 2000·Current Treatment Options in Neurology·D Lambert, C H Waters
Jul 29, 2000·Postgraduate Medicine·G Cooper, R Rodnitzky
Jul 4, 2006·CNS Spectrums·Frank M SkidmoreMichael S Okun
Jan 10, 2018·Acta Neurologica Scandinavica·C TuleascaD Van De Ville
Dec 29, 2020·Tremor and Other Hyperkinetic Movements·Anson WangAdolfo Ramirez-Zamora

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.