Effects of the Antibiotic Amoxicillin on Key Species of the Terrestrial Environment

Bulletin of Environmental Contamination and Toxicology
V D LitskasD S Koveos

Abstract

The antibiotic amoxicillin (AMX) is globally important for human and animal health. Although AMX is considered as a threat for the aquatic and terrestrial environment, limited data are present for its toxicity against key species such as denitrifying bacteria in soil, earthworms and plants. In the present research, the OECD protocols for environmental risk assessment were applied to study AMX acute toxicity, at nominal concentrations, close to the environmentally relevant, in soil bacteria responsible for nitrogen cycling, in the earthworm species Eisenia fetida and six plant species. The results revealed no significant effects of the antibiotic on the parameters related to the end-points of each respective test, at the selected concentration range. Therefore, the antibiotic did not present acute toxicity for the species, under the framework of the OECD tests. Further research is essential to be conducted also considering the patterns of degradation of AMX during the experimental periods.

References

Jan 1, 1977·Antimicrobial Agents and Chemotherapy·D A SpykerW M O'Brien
Jun 1, 1972·Antimicrobial Agents and Chemotherapy·C GordonW M Kirby
Jul 21, 2004·Ecotoxicology and Environmental Safety·M HendawiMichel Fournier
Mar 16, 2006·Journal of Agricultural and Food Chemistry·Alistair B A BoxallLen S Levy
Nov 10, 2007·FEMS Microbiology Ecology·Chu Thi Thanh BinhKornelia Smalla
Dec 7, 2007·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Tim ReynsSiska Croubels
Jul 16, 2014·The Lancet Infectious Diseases·Thomas P Van BoeckelRamanan Laxminarayan
Mar 23, 2018·BMJ Global Health·Andrew M HillDzintars Gotham

❮ Previous
Next ❯

Citations

Aug 27, 2019·Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering·Vassilis D LitskasDimitris S Koveos
Dec 22, 2019·Journal of Hazardous Materials·Mohammad Chahkandi, Mahboobeh Zargazi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.