Effects of the Gluten-free Diet on Body Mass Indexes in Pediatric Celiac Patients

Journal of Pediatric Gastroenterology and Nutrition
Karine AmirikianHilary Jericho

Abstract

The aim of the study was to determine the effects of the gluten-free diet (GFD) on body mass indexes (BMIs) in children with celiac disease at University of Chicago before and after 2011, when processed gluten-free foods became readily available on the market. We conducted a retrospective chart review of children seen at University of Chicago Celiac Center from January 2002 to May 2016. BMI was recorded upon GFD initiation in addition to at least 1 other timepoint: 6 months, 1 year, 2 years, 3 years, and 4+ years. We compared the rate of BMI increase in children who were diagnosed before versus after 2011. A total of 147 children (66% girls) with biopsy-confirmed celiac disease were included in the study. The mean BMI at diagnosis was 17.8 (standard deviation 3.9) for those diagnosed before 2011 and 17.1 (standard deviation 2.7) for those diagnosed after 2011. Based on a mixed-effects random-intercept random-slope regression model, there was no evidence for significant difference in BMI change over time between the 2 groups (P value = 0.36). BMI values overall were noted to increase after starting the GFD, even at the first appointment. Serologies were monitored after patients started the GFD and approached normal values, allow...Continue Reading

References

Jun 1, 2005·Best Practice & Research. Clinical Gastroenterology·M Luisa MearinWilliam Dickey
Oct 13, 2006·The American Journal of Gastroenterology·William Dickey, Natalie Kearney
Aug 19, 2010·European Journal of Clinical Nutrition·E VallettaC Danchielli
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Jan 8, 2014·JAMA Pediatrics·Stefano Guandalini, Asaad Assiri
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Nov 21, 2018·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Prashant Singh, Govind K Makharia

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Citations

Sep 23, 2020·Journal of Pediatric Gastroenterology and Nutrition·Joseph RundeHilary Jericho
Feb 3, 2021·Acta Paediatrica·Adi AnafyAnat Yerushalmy Feler

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