PMID: 39133Jun 1, 1979

Effects of the non-steroidal anti-inflammatory drug benoxaprofen on leucocyte migration

The Journal of Pharmacy and Pharmacology
S C Meacock, E A Kitchen

Abstract

Possible modes of action of the anti-inflammatory drug, benoxaprofen, have been explored. The drug caused inhibition of leucocyte migration, principally of mononuclear cells into the pleural cavity of rats undergoing carrageenan-induced pleurisy. Evidence was obtained from in vitro leucocyte migration and chemotaxis models that the drug acted directly on the mononuclear cells rather than by inhibition of chemotactic factors.

References

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Citations

Jul 1, 1982·Agents and Actions·I G OtternessJ G Lombardino
Feb 1, 1984·Agents and Actions·R AndersonG Jooné
Jan 10, 2012·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·Anjali PandeyKrishan Avtar Suri
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Nov 1, 1979·The Journal of Pharmacy and Pharmacology·J R Walker, W Dawson
May 1, 1992·The Journal of Pharmacy and Pharmacology·G B SinghS K Banerjee
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Nov 8, 2006·Journal of Ethnopharmacology·Sarang BaniGhulam Nabi Qazi
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May 17, 2005·Journal of Ethnopharmacology·Sarang BaniG N Qazi
Aug 14, 1982·British Medical Journal
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May 1, 1984·The Journal of Pharmacy and Pharmacology·E A Kitchen, W Dawson
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Dec 1, 1982·Arthritis and Rheumatism·E J Goetzl, F H Valone

Related Concepts

Anti-Inflammatory Agents
Benzoxazoles
Cell Motility
Chemotaxis, Leukocyte
Cavia porcellus
Differential White Blood Cell Count Procedure
Leukocytes
Pleurisy

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