PMID: 12770079May 29, 2003Paper

Effects of the polydnavirus of Cotesia congregata on the immune system and development of non-habitual hosts of the parasitoid

Journal of Insect Physiology
N LovalloD L. Cox-Foster

Abstract

Polydnaviruses (PDV) are obligate mutualistic symbionts found in association with some groups of parasitic Hymenoptera. In these groups, they suppress the immune response of the parasitoid's host and are required for successful parasitoid reproduction. Several PDV effects have been described in different experimental systems, but no clear picture of PDV mode of immunosuppression has emerged. No study to date has directly tested if PDV modes of action are evolutionarily conserved or divergent among parasitoid taxa within the Ichneumonoidea. We hypothesize the divergence in PDV mode of immunosuppression can be detected by identifying points of divergence in the immune response of different host species to PDV from one parasitoid species. This study tests the effects of purified PDV from Cotesia congregata on the immune response of three larval lepidopteran species that naturally are hosts of parasitoid species that differ in taxonomic relatedness to C. congregata. Here we demonstrate that despite associations with distantly related parasitoids (Ichneumonidae and Braconidae), Manduca sexta and Heliothis virescens showed similar patterns of increased glucose dehydrogenase (GLD) activity, suppressed cellular encapsulation in vitro, ...Continue Reading

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Citations

Aug 13, 2013·Journal of Invertebrate Pathology·V D'AmicoR Fuester
Nov 6, 2002·Journal of Invertebrate Pathology·Nancy E Beckage, Frances F Tan
Jul 25, 2003·Journal of Invertebrate Pathology·Nancy E BeckageFrances F Tan
Aug 18, 2009·Journal of Invertebrate Pathology·Li Luo, Ling Zeng
Nov 24, 2005·Archives of Insect Biochemistry and Physiology·Mario A Rodríguez-PérezNancy E Beckage
Dec 1, 2020·Molecular Phylogenetics and Evolution·Barbara J SharanowskiHeather M Hines

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