PMID: 2484385Mar 1, 1989Paper

Effects of thyroparathyroidectomy and of thyroxin and calcitonin on the tissue distribution of twelve elements in the rat

Biological Trace Element Research
G LeBlondel, P Allain

Abstract

The effects of thyroparathyroidectomy (TPTY) and of replacement therapy using thyroxin (T4) and calcitonin (CT) on the tissue distribution of elements were studied in the rat under semichronic conditions. The elements Na, K, Ca, Mg, Fe, S, P, Rb, Sr, Mn, Cu, and Zn were determined in whole blood, plasma, brain, liver, heart, kidney, skeletal muscle, and bone. TPTY modified concentrations of all elements tested but only small changes were observed for K, Mg, S, and P. The mineral bone composition was slightly modified, 28 d after TPTY, whereas plasma was the most altered. The consequences of TPTY were corrected fairly well by T4 for Na, Cu, Zn, Fe, and S, and by CT for K, P, Rb but with less efficiency for Ca. This study revealed that hormones of the thyroid gland, mainly T4, play an important role in the plasma and tissue balance of elements. It is suggested that T4 participates in tissue fixation of Cu, Zn, and Fe and that CT influences phosphoremia and cellular Ca binding.

References

Dec 25, 1976·Lancet·R SwaminathanD B Morgan
Mar 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·G N DeMartino, A L Goldberg
Sep 1, 1978·Journal of Toxicology and Environmental Health·S L FeldmanR J Cousins
Jun 14, 1976·Calcified Tissue Research·P Cuisnier-GleizesH Mathieu
Jun 1, 1988·Biological Trace Element Research·G LeBlondel, P Allain
Sep 1, 1985·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A B Bomford, H N Munro
Jul 1, 1986·Physiological Reviews·T Clausen
Jun 1, 1985·Acta Endocrinologica·R C PercivalJ A Kanis
Jun 14, 1985·Biochemical and Biophysical Research Communications·K NaitoY Sakamoto
Apr 1, 1973·The Journal of Clinical Investigation·A I Katz, M D Lindheimer
Nov 1, 1973·The American Journal of Physiology·F Ismail-Beigi, I S Edelman
Apr 1, 1967·Clinica Chimica Acta; International Journal of Clinical Chemistry·D E FrizelV Marks
Dec 1, 1984·Pharmacological Research Communications·E RapisardaU Scapagnini
May 1, 1982·Annals of Internal Medicine·C I Macaron, Z G Macaron
Dec 1, 1980·Postgraduate Medical Journal·Y NishiT Usui
May 1, 1932·The Journal of Clinical Investigation·A LockeD O Rosbash
Oct 1, 1986·Biological Trace Element Research·G LeblondelP Allain

❮ Previous
Next ❯

Citations

Jan 1, 1992·Biological Trace Element Research·P Allain, G Leblondel
Feb 1, 1996·Biological Trace Element Research·K YokoiY Itokawa
Mar 7, 2008·Biological Trace Element Research·Muhammed ErdalKenan Saglam
Dec 31, 2003·Toxicology·Abdulkerim Kasim BaltaciAysegul Ugur
Aug 8, 2008·Biological Trace Element Research·Fatima HammoudaAbdelhamid Kerkeni
Nov 10, 2006·Cell Biochemistry and Function·Muaz Belviranli, Abdulkerim Kasim Baltaci
Dec 20, 2003·Endocrine Research·Abdulkerim Kasim BaltaciAysegul Ugur

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.