May 1, 1977

Effects of topical anesthetics on phenylephrine-induced mydriasis

American Journal of Optometry and Physiological Optics
W M Lyle, W R Bobier

Abstract

Pupil responses to phenylephrine alone and to phenylephrine preceded by a topical anesthetic were recorded by means of an infrared pupillometer. In response to phenylephrine, pupils dilated more in eyes with pale irides. Dilation was greater if a topical anesthetic was applied before the mydriatic. Benoxinate, proparacaine, and tetracaine produced approximately equal degrees of enhancement of the mydriasis. One drop of 1% phenylephrine had only a small dilating effect on an eye when the fellow eye received the phenylephrine preceded by 0.5% proparacaine.

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Mentioned in this Paper

Phenylephrine Hydrochloride
Cycloplegics
Pontocaine
Administration, Topical
Topical anesthetic
Pupil

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