PMID: 11909022Mar 23, 2002Paper

Effects of torsional strain on thermal denaturation of DNA

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics
Joseph Rudnick, Robijn Bruinsma

Abstract

A class of simple statistical mechanical models for DNA melting, first proposed by Poland and Scheraga, has been demonstrated to exhibit a first or second order thermodynamic singularity, notwithstanding the intrinsic one-dimensional nature of the problem. In the present paper we consider the case of circular DNA and show that the inclusion of twist elastic energy in the Poland-Scheraga models leads either to suppression of the thermodynamic singularity or to a weak, third order singularity. Such behavior may also be present in linear DNA under mechanical influences that preclude the release of torsional strain.

References

Sep 1, 1966·The Journal of Chemical Physics·D Poland, H A Scheraga
Sep 1, 1966·The Journal of Chemical Physics·D Poland, H A Scheraga
Dec 17, 1981·Nature·A V Gagua Lyubchenko YuL
Dec 20, 1993·Journal of Molecular Biology·W R Bauer, C J Benham
Jan 23, 1999·Biophysical Chemistry·S KunduA R Thakur
Jun 5, 1989·Physical Review Letters·M Peyrard, A R Bishop
Jun 28, 2000·Nucleic Acids Research·V VíglaskýD Podhradský
Sep 6, 2000·Physical Review Letters·D K Lubensky, D R Nelson
Dec 2, 2000·Physical Review Letters·Y KafriL Peliti
Feb 13, 2001·Biophysical Journal·I Rouzina, V A Bloomfield
Feb 13, 2001·Biophysical Journal·I Rouzina, V A Bloomfield

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Citations

Nov 10, 2006·The Journal of Chemical Physics·Jae-Hyung JeonWokyung Sung
Oct 26, 2010·The Journal of Chemical Physics·M BaiesiD Panja
May 6, 2006·The Journal of Chemical Physics·Jae-Hyung JeonFrancis H Ree
Jan 6, 2006·The Journal of Chemical Physics·Shirish M Chitanvis, Paul M Welch
Jul 23, 2008·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Joseph Rudnick, Tatiana Kuriabova
May 21, 2010·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Mehmet SayarAlkan Kabakçioğlu
Sep 28, 2017·Physical Review Letters·Y A G FosadoD Marenduzzo
Apr 20, 2004·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Wokyung Sung, Jae-Hyung Jeon
Feb 2, 2013·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Amir BarDavid Mukamel
Jul 13, 2004·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·J Cuevas, P G Kevrekidis
Aug 8, 2009·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·A KabakçioğluD Mukamel
Sep 26, 2012·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Alkan KabakçıoğluDavid Mukamel
Dec 21, 2011·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Amir BarDavid Mukamel

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