Effects of Transcranial Direct Current Stimulation (tDCS) and Approach Bias Modification (ABM) training on food cravings in people taking antipsychotic medication

Trials
Luiza GrycukUlrike Schmidt

Abstract

Antipsychotic drug-induced weight gain puts individuals with schizophrenia at increased cardiometabolic risk. As a potential intervention for this problem, we describe the theoretical background and a protocol for a feasibility randomised controlled trial (RCT) of approach bias modification (ABM) training combined with real versus sham (placebo) transcranial direct current stimulation (tDCS). The primary aim of this trial is to obtain information that will guide decision making and protocol development in relation to a future large-scale RCT of ABM and tDCS in this group of participants. Second, the study will assess the preliminary efficacy of ABM + tDCS in reducing food cravings in people who take antipsychotic medication. Thirty adults with a DSM-V diagnosis of schizophrenia or schizoaffective disorder treated with anti-psychotic medication will be randomly allocated to receive five sessions that will combine ABM and real or sham tDCS, in a parallel group design. In this feasibility study, a broad range of outcome variables will be examined. Measures will include food craving, psychopathology (e.g. symptoms of schizophrenia and depression), neuropsychological processes (such as attentional bias and impulsiveness), and the to...Continue Reading

References

Nov 1, 1995·Journal of Clinical Psychology·J H PattonE S Barratt
Mar 10, 1998·Molecular Psychiatry·T BrömelJ Hebebrand
Aug 12, 1999·Acta Psychiatrica Scandinavica·T Baptista
Jun 1, 2000·The American Journal of Psychiatry·D C HendersonD C Goff
Oct 21, 2000·The British Journal of Psychiatry : the Journal of Mental Science·S BrownB Barraclough
Jan 24, 2003·Journal of Neural Transmission·F M TheisenJ Hebebrand
Jun 11, 2004·Journal of Evaluation in Clinical Practice·Gillian A LancasterPaula R Williamson
Jan 7, 2005·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Del D MillerStephan Arndt
Apr 9, 2005·Journal of the American Geriatrics Society·Ziad S NasreddineHoward Chertkow
Jan 12, 2010·Biological Psychiatry·Frederique Van den EyndeUlrike Schmidt
Mar 26, 2010·BMC Medicine·Kenneth F SchulzUNKNOWN CONSORT Group
Jul 1, 2008·Brain Stimulation·Michael A NitscheAlvaro Pascual-Leone
Feb 16, 2011·The International Journal of Neuropsychopharmacology·Andre Russowsky BrunoniFelipe Fregni
Feb 24, 2011·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Charlotte J Stagg, Michael A Nitsche
May 4, 2011·International Journal of Methods in Psychiatric Research·André Russowsky Brunoni, Felipe Fregni
Sep 2, 2011·European Psychiatry : the Journal of the Association of European Psychiatrists·F Van den EyndeU Schmidt
Aug 8, 2012·Archives of General Psychiatry·Jose MathewsDeanna M Barch
Nov 17, 2012·Journal of Psychiatric Research·Salvatore DipasqualeValeria Mondelli
Jan 9, 2013·Annals of Internal Medicine·An-Wen ChanDavid Moher
Aug 7, 2013·Neuroscience and Biobehavioral Reviews·Jochem M JansenAnna E Goudriaan
Sep 3, 2013·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·André Russowsky BrunoniFelipe Fregni
Jul 11, 2014·Frontiers in Psychology·Jens BlechertKathrin Ohla
Sep 6, 2014·Trends in Endocrinology and Metabolism : TEM·Jacob S BallonJeffrey A Lieberman
Nov 13, 2015·Acta Psychiatrica Scandinavica·S D ØstergaardP Bech
Feb 26, 2016·Frontiers in Neuroscience·Katharine A DunlopJonathan Downar
Apr 9, 2016·The British Journal of Psychiatry : the Journal of Mental Science·André R BrunoniColleen K Loo

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Methods Mentioned

BETA
cognitive behavioural therapy

Clinical Trials Mentioned

ISRCTN13280178

Software Mentioned

Sealed Envelope

Related Concepts

Related Feeds

Antipsychotic-Induced Weight Gain

Antipsychotic-induced weight gain (aiwg) is a common adverse effect of this treatment, particularly with second-generation antipsychotics, and it is a major health problem around the world. Here are the latest discoveries pertaining to AIWG.

Antipsychotic Drugs

Antipsychotic drugs are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder. Discover the latest research on antipsychotic drugs here