Effects of transdermal magnesium chloride on quality of life for patients with fibromyalgia: a feasibility study

Journal of Integrative Medicine
Deborah J EngenDietlind L Wahner-Roedler

Abstract

Fibromyalgia is a syndrome characterized by chronic pain, fatigue, depression, and sleep disturbances. Its primary cause is unclear. Several studies have reported decreased intracellular magnesium levels in patients with fibromyalgia and have found negative correlation between magnesium levels and fibromyalgia symptoms. To gather preliminary data on whether transdermal magnesium can improve quality of life for women who have fibromyalgia. This is a patient questionnaires and survey in a fibromyalgia clinic at a tertiary medical center. Forty female patients with the diagnosis of fibromyalgia were enrolled. Each participant was provided a spray bottle containing a transdermal magnesium chloride solution and asked to apply 4 sprays per limb twice daily for 4 weeks. Participants were asked to complete the Revised Fibromyalgia Impact Questionnaire, SF-36v2 Health Survey, and a quality-of-life analog scale at baseline, week 2, and week 4. Questionnaire and survey scores, evaluated through intent-to-treat and per-protocol analyses. Twenty-four patients completed the study (mean [SD] age, 57.2 [7.6] years; white, 95%; mean body mass index, 31.3 kg/m2). With intention-to-treat analysis, Revised Fibromyalgia Impact Questionnaire subscal...Continue Reading

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Citations

Mar 5, 2019·Current Rheumatology Reports·Amit PrabhakarAlan D Kaye
Dec 18, 2019·Current Drug Delivery·Karna B Ghimirey, Kevin Ita
Apr 14, 2019·Molecular Diversity·Toktam Shiebani Daloee, Farahnaz K Behbahani
Jun 9, 2018·Nutrients·Anna E KirklandKathleen F Holton
Jul 28, 2020·Nutrients·Emily K TarletonBenjamin Littenberg
Aug 23, 2020·Nutrients·Giuditta PagliaiBarbara Colombini
Jul 29, 2020·Nutrients·Hyun-Jung ShinSang-Hwan Do
Jul 7, 2017·Journal of the American College of Nutrition·Jane M HightowerGermán T Hernández
Aug 17, 2021·Journal of Primary Care & Community Health·Michael BoulisDaniel Clauw
Apr 21, 2018·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Geir BjørklundJan Aaseth

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