Effects of transient acute kidney injury, persistent acute kidney injury and acute kidney disease on the long-term renal prognosis after an initial acute kidney injury event.

Nephrology
Keitaro NagataYoshiyasu Okuhara

Abstract

To clarify the effects of the duration of acute damage and/or loss of renal function following an acute kidney injury event on the renal prognosis after recovery. We retrospectively reviewed data collected between 1995 and 2016 from the Kochi Medical School Hospital. Patients were stratified according to the time required for recovery with fluid therapy (expected to reflect the presence of renal dysfunction): ≤2 days after onset, transient injury group (n = 491); 3 to 7 days after onset, persistent injury group (n = 1076); and ≥ 8 days after onset, acute kidney disease group (n = 1046). The healthy group comprised 1000 randomly selected adult patients without acute kidney injury with at least two creatinine measurement results during the study. Survival time was defined as the time from recovery to a 30% decrease in the estimated glomerular filtration rate (primary endpoint). Kaplan-Meier and Cox proportional hazards analyses were conducted. Event incidence rates were higher for the transient injury, persistent injury and acute kidney disease groups than for the healthy group. Persistent injury and acute kidney disease presented a higher risk of renal function decline than transient injury following recovery. Transient acute ki...Continue Reading

References

Apr 30, 2002·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Kevin NashSusan Hou
Apr 3, 2009·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Seiichi MatsuoUNKNOWN Collaborators developing the Japanese equation for estimated GFR
Jan 8, 2010·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Shigehiko UchinoDonna Goldsmith
Sep 28, 2010·The Annals of Thoracic Surgery·Jeremiah R BrownChirag R Parikh
Oct 29, 2010·Nature Reviews. Nephrology·Chirag R Parikh, Steven G Coca
Mar 16, 2012·Kidney International·Maryam NejatZoltán H Endre
Aug 3, 2012·Kidney International·Kent DoiEisei Noiri
Jul 6, 2014·The New England Journal of Medicine·Lakhmir S ChawlaPaul L Kimmel
Mar 27, 2015·Journal of the American Society of Nephrology : JASN·Manjeri A VenkatachalamAnil K Bidani
Feb 28, 2017·Nature Reviews. Nephrology·Lakhmir S ChawlaUNKNOWN Acute Disease Quality Initiative Workgroup 16.
Apr 11, 2018·Clinical and Experimental Nephrology·Yutaka HatakeyamaYoshiyasu Okuhara

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Related Feeds