Effects of treadmill exercise on muscle fibers in mice with steroid myopathy

Journal of the Japanese Physical Therapy Association = Rigaku Ryōhō
M OkitaK Eguchi

Abstract

We studied the effect of treadmill exercise on muscle fibers in mice with experimental steroid myopathy. Frozen sections of the extensor digitorum longus (EDL) and soleus (SOL) muscles were stained with hematoxylin-eosin, and the muscle fiber diameters measured. In the EDL, muscle fiber diameters in the steroid groups decreased significantly compared with those in the control groups; moreover, muscle fiber diameters in the exercise groups increased significantly compared with those in the non-exercise groups, whereas the diameters in the SOL did not differ. We speculate that treadmill exercise may prevent corticosteroid-induced muscle fiber atrophy.

References

Jan 1, 1979·European Journal of Applied Physiology and Occupational Physiology·M KrotkiewskiL Sjöström
Jan 1, 1977·Molecular and Cellular Endocrinology·S Shoji, R J Pennington
Apr 1, 1990·Journal of Muscle Research and Cell Motility·H Takekura, T Yoshioka
Jan 1, 1989·European Journal of Applied Physiology and Occupational Physiology·M V NariciP Cerretelli
Jul 1, 1985·The Journal of Clinical Endocrinology and Metabolism·F F HorberF J Frey
Oct 1, 1974·Experimental Neurology·S ShojiY Toyokura
May 1, 1980·Pflügers Archiv : European journal of physiology·P F GardinerV R Edgerton
Apr 1, 1964·Journal of Cellular Physiology·G GOLDSPINK

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Citations

Aug 2, 2017·Pflügers Archiv : European journal of physiology·Hiroyasu SakaiMinoru Narita

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