Effects of two different oral contraceptives on total body water: a randomized study

Contraception
Rogério Bonassi MachadoEdna Maia

Abstract

This open-label, randomized study evaluated the effect of two different oral contraceptives on body weight and composition during one cycle of treatment. Eighty women (mean age, 24.6 years) were randomized into three groups and given one of the following contraceptive methods: ethinylestradiol 15 mug/gestodene 60 mug (EE/GST, n=25), ethinylestradiol 30 mug/drospirenone 3 mg (EE/DRS, n=29) or male condom (control group, n=26). Bioelectric impedance analysis (BIA) was carried out on the first, 10th and 21st days during the use of oral contraceptives or in the menstrual cycle (control group), and total body water (TBW), fat mass (FM) and fat-free mass (FFM) were measured. No significant variations in TBW, FM or FFM were observed in the three groups during the cycle. Intergroup analysis showed no differences in TBW or FM; however, users of EE/GST showed a statistically significant increase in FFM compared to the control group. The different doses of ethinylestradiol associated with gestodene or drospirenone showed no statistically significant effects on TBW or FM during one cycle of observation.

References

Nov 1, 1976·The Journal of Clinical Endocrinology and Metabolism·W OelkersJ Hammerstein
Sep 18, 1967·JAMA : the Journal of the American Medical Association·J H LaraghM A Newton
Nov 1, 1995·The Medical Clinics of North America·K T BarnhartS J Sondheimer
Aug 3, 2000·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·W OelkersR Heithecker
Oct 9, 2002·Homo : internationale Zeitschrift für die vergleichende Forschung am Menschen·E Gualdi-Russo, S Toselli
May 3, 2003·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·D ApterS Kelly
May 12, 2004·Molecular and Cellular Endocrinology·Wolfgang Oelkers

❮ Previous
Next ❯

Citations

Jun 27, 2008·Medicine and Science in Sports and Exercise·Elizabeth Procter-GrayJennifer L Kelsey
Dec 24, 2010·Women's Health·Rogério Bonassi MachadoCassiana Galvão Giribela
Oct 24, 2006·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·Inka Wiegratz, Herbert Kuhl
Jan 31, 2014·The Cochrane Database of Systematic Reviews·Maria F GalloFrans M Helmerhorst
Sep 9, 2020·Revista brasileira de ginecologia e obstetrícia : revista da Federação Brasileira das Sociedades de Ginecologia e Obstetrícia·Joyce Beatriz da SilvaJúlio Rosa-E-Silva Silva

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.