Effects of ultraviolet radiation on respiration and growth in radiation-resistant and radiation-sensitive strains of Escherichia coli B.

Journal of Bacteriology
B A Hamkalo, P A Swenson

Abstract

Ultraviolet (UV) irradiation at 254 nm causes different respiration and growth responses in log-phase cultures of Escherichia coli B/r and B(s-1). These differences are correlated with the ability and inability, respectively, of these bacterial strains to repair UV-induced lesions in deoxyribonucleic acid (DNA). After irradiation, B(s-1) cells (radiation-sensitive) exhibit uncoupling of growth and respiration; growth and synthesis cease, whereas respiration continues. B/r cells (radiation-resistant) grown on glycerol exhibit severe temporary inhibition of growth and respiration after UV, and the coupling of these two processes is maintained, except at a very high UV dose. Inhibition begins at about the time DNA synthesis resumes and continues for a period of time that is dependent upon dose. Glucose-grown cells do not exhibit severe respiratory, growth, and synthetic inhibitions; these processes remain coupled in the cells during the postirradiation period. Photoreactivation treatment delays uncoupling of growth and respiration in B(s-1) and prevents inhibition of respiration and growth in B/r. These results indicate that the postirradiation responses result from the presence of pyrimidine dimers in DNA. Ultraviolet irradiation...Continue Reading

References

Jul 1, 1967·Mutation Research·K Haefner, U Striebeck
Nov 12, 1965·Science·D E Atkinson
Jan 1, 1966·Journal of Molecular Biology·P A Swenson, R B Setlow
Jul 1, 1953·Biochimica Et Biophysica Acta·D KANAZIR, M ERRERA
Feb 1, 1964·Proceedings of the National Academy of Sciences of the United States of America·R B SETLOW, W L CARRIER
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Feb 1, 1949·Proceedings of the National Academy of Sciences of the United States of America·A Kelner

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Citations

Jan 1, 1974·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·P A Swenson, R L Schenley
Jan 1, 1974·Photochemistry and Photobiology·P A SwensonR L Schenley
Oct 1, 1974·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·D K Myers, L D Johnson
Jan 1, 1971·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·P A SwensonJ M Boyle
Jan 1, 1971·Zeitschrift für allgemeine Mikrobiologie·F Kössler

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