Effects of Vaccinium Berries on Serum Lipids: A Meta-Analysis of Randomized Controlled Trials

Evidence-based Complementary and Alternative Medicine : ECAM
Yitong ZhuYuan Zhong

Abstract

The beneficial effects of anthocyanins consumption on cardiovascular risk are supported by mechanistic and epidemiologic evidence. In order to explore the effects of Vaccinium berries rich in anthocyanins on serum lipids, we conducted a meta-analysis of relevant randomized controlled trials (RCTs). Sixteen studies with 1109 subjects were included in this meta-analysis. Significant heterogeneity confirmed differential effects between Vaccinium subclasses. The whortleberry group is significantly superior to placebo in lipids improvement. Besides, bilberry groups show significant differences in reducing LDL-C and increasing HDL-C in comparison with other treatments. For many of the other subgroups and comparison arms, there was insufficient evidence to draw conclusions about efficacy.

References

Jan 7, 2004·Journal of Agricultural and Food Chemistry·Tony K McGhieDwayne J Jensen
May 28, 2004·Pharmacotherapy·Simon de DenusAndrew M Peterson
Feb 17, 2005·Journal of Agricultural and Food Chemistry·Patrizia RisoMarisa Porrini
Jul 25, 2006·Bioscience, Biotechnology, and Biochemistry·Ryoko OhnishiTakashi Yoshida
May 12, 2007·Molecular Nutrition & Food Research·Ruth G Jepson, Jonathan C Craig
Feb 9, 2008·The American Journal of Clinical Nutrition·Iris ErlundAntti Jula
Dec 3, 2008·Diabetic Medicine : a Journal of the British Diabetic Association·I T LeeW H-H Sheu
Mar 21, 2009·Journal of Medicinal Food·Anastasia Z KaleaDorothy J Klimis-Zacas
Dec 24, 2009·International Journal of Obesity : Journal of the International Association for the Study of Obesity·L TittaM Giorgio
Jul 28, 2010·The Journal of Nutrition·Arpita BasuTimothy J Lyons
Aug 21, 2010·The Journal of Nutrition·April J StullWilliam T Cefalu
Mar 18, 2011·The American Journal of Clinical Nutrition·Mustali M DohadwalaJoseph A Vita
Sep 8, 2011·Current Opinion in Lipidology·David Preiss, Naveed Sattar
Feb 22, 2012·International Journal of Clinical Practice·A S WierzbickiA Viljoen
Jun 22, 2012·The American Journal of Cardiology·Antonio M Gotto, Jennifer E Moon
Aug 22, 2012·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Y ZhuY Yang
Nov 26, 2013·Lancet·Paul M Ridker, Nancy R Cook
Jan 10, 2014·Diabetes & Metabolism Journal·Ji Sung Yoon, Hyoung Woo Lee
Feb 18, 2014·Translational Research : the Journal of Laboratory and Clinical Medicine·Dhiaa A TahaPavel Gershkovich

❮ Previous
Next ❯

Software Mentioned

RevMan
Review Manager (

Related Concepts

Related Feeds

ApoE, Lipids & Cholesterol

Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.