Effects of Vaccinium Berries on Serum Lipids: A Meta-Analysis of Randomized Controlled Trials
Abstract
The beneficial effects of anthocyanins consumption on cardiovascular risk are supported by mechanistic and epidemiologic evidence. In order to explore the effects of Vaccinium berries rich in anthocyanins on serum lipids, we conducted a meta-analysis of relevant randomized controlled trials (RCTs). Sixteen studies with 1109 subjects were included in this meta-analysis. Significant heterogeneity confirmed differential effects between Vaccinium subclasses. The whortleberry group is significantly superior to placebo in lipids improvement. Besides, bilberry groups show significant differences in reducing LDL-C and increasing HDL-C in comparison with other treatments. For many of the other subgroups and comparison arms, there was insufficient evidence to draw conclusions about efficacy.
References
Vascular reactivity is affected by dietary consumption of wild blueberries in the Sprague-Dawley rat
Effects of cranberry juice consumption on vascular function in patients with coronary artery disease
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