PMID: 3747732Sep 1, 1986Paper

Effects of vanadium on reproduction, gestation, parturition and lactation in rats upon oral administration

Life Sciences
J L DomingoJ Corbella

Abstract

Sodium metavanadate was tested for its effects on fetal development, reproduction, gestation and lactation in Sprague Dawley rats. Male rats were administered NaVO3 po at doses of 0, 5, 10 and 20 mg/kg/day for sixty days before mating with females which had received the same doses from 14 days previous to mating. These females received 0, 5, 10 and 20 mg NaVO3/kg/day during the periods of gestation and lactation. No significant adverse effects could be observed on: number of corpora lutea, implantations, live and dead fetuses, and resorptions. Significant decreases were observed in the development of the pups in all the vanadium -treated groups. All the doses used produced toxic effects in the offspring.

References

Oct 26, 1978·Nature·W E BalfourI M Glynn
Dec 1, 1985·Journal of Applied Toxicology : JAT·J L DomingoJ Corbella
Mar 1, 1972·Toxicology and Applied Pharmacology·E J Gralla, H M McIlhenny
Feb 1, 1973·Food and Cosmetics Toxicology·V J FeronH P Til
Nov 1, 1984·Toxicology Letters·J M Llobet, J L Domingo
Jan 1, 1983·Toxicology·M HeideG F Fuhrmann
Aug 6, 1981·Biochimica Et Biophysica Acta·T RamasarmaF L Crane
Oct 1, 1982·Journal of Toxicology and Environmental Health·C I WeiL D Hansen
Oct 1, 1963·Journal of Chronic Diseases·H A SCHROEDERI H TIPTON

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Citations

Jun 1, 1990·Journal of Applied Toxicology : JAT·J L PaternainJ Corbella
Sep 1, 1991·Biological Trace Element Research·D SanchezJ Corbella
Jun 11, 1993·Toxicology·J M LlobetJ Corbella
Jan 1, 1989·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·H Zaporowska, W Wasilewski
May 1, 1996·Reproductive Toxicology·J L Domingo
Apr 6, 2005·Reproductive Toxicology·M A AragónM Altamirano-Lozano
Apr 6, 2013·Neurotoxicology and Teratology·Santiago CuestaGraciela Beatriz García
Jun 26, 1999·Journal of Toxicology. Clinical Toxicology·D G Barceloux
May 12, 2007·Neurotoxicology and Teratology·Marina Soazo, Graciela Beatriz Garcia

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