PMID: 8120477Jan 1, 1994Paper

Effects of volatile anesthetics, enflurane, isoflurane, and halothane on ventricular delayed activation in a canine myocardial infarction model

Journal of Electrocardiology
S ImamuraM Nakashima

Abstract

The authors examined the effects of volatile anesthetics (enflurane, isoflurane, and halothane) on ventricular activation in a canine myocardial infarction model. Enflurane at 1 minimum aveolar concentration further delayed or blocked delayed activation in the infarcted zones with only slight effects on activation of the normal zones. Halothane showed similar and comparable effects on ventricular activation to those of enflurane. Although isoflurane also showed similar effects, they were of a lesser extent. Enflurane and halothane, but not isoflurane, inhibited ventricular stimulation-induced arrhythmias. Thus, enflurane and halothane produced marked depression of delayed activation in myocardial infarction, which may affect, that is, inhibit or provoke, ventricular arrhythmias in myocardial infarction.

References

Nov 14, 1977·Biochimica Et Biophysica Acta·L M Hondeghem, B G Katzung
May 1, 1977·Anesthesia and Analgesia·J L Atlee, S C Alexander
Dec 1, 1990·Naunyn-Schmiedeberg's Archives of Pharmacology·H HashimotoM Nakashima
Jan 1, 1986·The Japanese Journal of Physiology·Y IkemotoH Arimura
Jun 1, 1988·British Journal of Pharmacology·D A Terrar, J G Victory
May 1, 1980·Anesthesia and Analgesia·L A TurnerJ P Kampine
Oct 1, 1981·Anesthesiology·C LynchN Sperelakis

❮ Previous
Next ❯

Citations

Jul 30, 2003·Pharmacotherapy·Michael A CrouchAngela T Cassano
Apr 16, 2002·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Harriette J KahnAlexander Marks
Nov 10, 1998·Journal of Personality Assessment·J L PearsonN L Kamptner
Feb 24, 2012·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Eileen K Graham, Margie E Lachman

❮ Previous
Next ❯

Related Concepts

Related Feeds

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Cardiac Conduction System

The cardiac conduction system is a specialized tract of myocardial cells responsible for maintaining normal cardiac rhythm. Discover the latest research on the cardiac conduction system here.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.