Effects of volatile components and ethanolic extract from Eclipta prostrata on proliferation and differentiation of primary osteoblasts.

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Xiong-Hao LinJin-Zhong Wu

Abstract

Eclipta prostrata, an aromatic plant, is known in Chinese herbal medicine for the treatment of various kidney diseases. In the present study, the volatile components were isolated from the aerial parts of this plant by hydrodistillation and analysed by GC-MS. A total of 55 compounds, which were the major part (91.7%) of the volatiles, were identified by matching mass spectra with a mass spectrum library (NIST 05.L). The main components were as follows: heptadecane (14.78%), 6,10,14-trimethyl-2-pentadecanone (12.80%), n-hexadecanoic acid (8.98%), pentadecane (8.68%), eudesma-4(14),11-diene (5.86%), phytol (3.77%), octadec-9-enoic acid (3.35%), 1,2-benzenedicarboxylic acid diisooctyl ester (2.74%), (Z,Z)-9,12-octadecadienoic acid (2.36%), (Z)-7,11-dimethyl-3-methylene-1,6,10-dodecatriene (2.08%) and (Z,Z,Z)-1,5,9,9-tetramethyl-1,4,7-cycloundecatriene (2.07%). The effects of volatile components and ethanolic extract from the aerial parts of this plant on the proliferation and differentiation of primary osteoblasts were evaluated by the MTT method and measuring the activity of alkaline phosphatase (ALP activity). Both volatile components and ethanolic extract (1 microg/mL to 100 microg/mL) significantly (p < 0.01) stimulated the pr...Continue Reading

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Citations

Sep 13, 2011·Chinese Journal of Integrative Medicine·Xian-xiang LiuJian Du
Aug 24, 2011·Natural Product Research·Xiaoqin WangXuewu Zhang
Dec 25, 2012·BMC Complementary and Alternative Medicine·Mengfei LiWei Li
Mar 8, 2016·Journal of Invertebrate Pathology·Sivalingam ManjuBaskaralingam Vaseeharan
Mar 2, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Chun-Tao CheChristopher Wai Kei Lam
Apr 1, 2014·TheScientificWorldJournal·Chin-Feng ChanBo Rong Wang
Jul 1, 2017·The American Journal of Chinese Medicine·Dae-Seung KimSeung-Heon Hong
Feb 2, 2019·Journal of the Science of Food and Agriculture·Yiru ZhangHongying Li
May 23, 2019·Journal of Complementary & Integrative Medicine·Samson GuennéMartin Kiendrebéogo

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