Effects of weight change on clinical outcomes in overweight and obese patients with acute myocardial infarction who underwent successful percutaneous coronary intervention.

Chonnam Medical Journal
Won Yu KangMyung Ho Jeong

Abstract

Obesity is a well-established risk factor for many chronic disorders. However, the effect of weight change after acute myocardial infarction (AMI) is not well known. Among consecutive patients who underwent percutaneous coronary intervention between November 2005 and November 2007 due to AMI, patients who were overweight (23.0≤body mass index [BMI]<27.5 kg/m(2), n=341) and obese (BMI≥27.5 kg/m(2), n=80) were selected for analysis. According to weight change, the patients were divided into 4 groups: Group I (weight loss>5%, n=61), Group II (0%<weight loss≤5%, n=133), Group III (0%≤weight gain<5%, n=181), and Group IV (weight gain≥5%, n=46). We assessed the association between weight change and major adverse cardiac events (MACE). Greater weight loss was more frequent among older individuals (Group I: 64.1±12.4 years, II: 60.6±12.1 years, III: 59.0±11.9 years, IV: 61.4±10.6 years; p=0.028) and patients with diabetes (Group I: 34.4%, II: 27.1%, III: 21.2%, IV: 15.2%; p=0.009). However, there were no significant differences in baseline characteristics or in angiographic or procedural factors except for the proportions of patients with three-vessel disease, which were higher in patients with weight loss (Group I: 20.8%, II: 23.0%, I...Continue Reading

References

Jul 20, 1999·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·D B AllisonS B Heymsfield
Mar 16, 2001·The American Journal of Cardiology·K DicksteinUNKNOWN OPTIMAAL Trial Steering Committee and Investigators. Optimal Trial in Myocardial Infarction with the Angiotensin II Antagoni
Aug 31, 2001·Journal of the American College of Cardiology·T B HorwichJ H Tillisch
Feb 16, 2002·Heart·N T Mulvihill, J B Foley
Feb 19, 2002·Journal of the American College of Cardiology·Luis GrubergJoseph Lindsay
May 3, 2002·Journal of the American College of Cardiology·Carl J LavieFranz H Messerli
Jun 29, 2002·The American Journal of Cardiology·Hitinder S GurmEric J Topol
Jan 29, 2005·International Journal of Cardiology·Charlotte KragelundUNKNOWN TRACE study group
Jun 20, 2007·European Heart Journal·Heinz J BuettnerFranz-Josef Neumann
Sep 26, 2007·American Heart Journal·Yazid Y FadlJohn A Spertus
May 23, 2009·Journal of the American College of Cardiology·Carl J LavieHector O Ventura
Feb 4, 2010·Journal of cardiology·Won Yu KangUNKNOWN Korea Acute Myocardial Infarction Registry Investigators

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Citations

Oct 31, 2014·European Journal of Epidemiology·Jacek NiedzielaPiotr Rozentryt
Sep 10, 2014·Mayo Clinic Proceedings·Quinn R PackFrancisco Lopez-Jimenez

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Methods Mentioned

BETA
coronary artery bypass

Software Mentioned

OPTIMAAL
SPSS
CONSENSUS

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