PMID: 9557799Apr 29, 1998Paper

Effects of weight gain and loss on metabolic rate, glucose tolerance, and serum lipids in domestic cats

Research in Veterinary Science
M J FettmanS Johnston

Abstract

Weight gain is a common problem in domestic cats, but little is known about its metabolic effects. The purpose of this study was to determine the effects of diet-induced weight gain and subsequent weight loss on metabolic rate, body composition, and glucose tolerance. Gain of approximately 20 per cent body weight (divided approximately equally between fat and fat-free mass) over three months resulted in insulin resistance in females, indicated by increases in basal insulin concentration (68.2+/-7.9 to 119+/-16.5 pmol litre(-1), P<0.05), insulin peak response to glucose (241.1+/-31.6 to 315.0+/-23.0 pmol litre(-1), P<0.05), and deltaI/deltaG (14.2+/-2.6 to 18.1+/-1.3 pmol mmol(-1), P<0.05) compared with pre-gain values. The same numerical trend was noted in male cats, however, changes were not significant (P>0.05). Alterations in serum lipids included significant (P<0.05) elevations in triglyceride concentrations in male cats and decreased beta-lipoprotein concentrations in both genders. Weight loss over three months normalised basal insulin, insulin response to glucose, and serum triglyceride concentrations, and resulted in significant (P<0.05) decreases in serum concentrations of beta- and prebeta-lipoproteins, cholesterol, an...Continue Reading

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Mar 1, 1997·Research in Veterinary Science·M J FettmanS Johnston

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Citations

Jul 29, 2000·Preventive Veterinary Medicine·F J AllanM S Wiseman
Jun 18, 2002·European Journal of Internal Medicine·J Bilbao-GarayC Guijarro
Jun 29, 2006·ILAR Journal·Michael S Henson, Timothy D O'Brien
Jan 6, 2005·American Journal of Veterinary Research·Patrick G NguyenVincent C Biourge
Sep 4, 2008·Journal of the American Veterinary Medical Association·Philip RoudebushSean J Delaney
Jul 21, 2012·Journal of Animal Physiology and Animal Nutrition·T HäringB A Wichert
Jul 17, 2015·Journal of Veterinary Internal Medicine·M ÖhlundA Egenvall
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Mar 12, 2010·The Veterinary Clinics of North America. Small Animal Practice·Dong Yong Kil, Kelly S Swanson

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