Effects of xylazine hydrochloride on hormonal, metabolic, and cardiorespiratory stress responses to lateral recumbency and claw trimming in dairy cows

Journal of the American Veterinary Medical Association
Awad RizkJuergen Rehage

Abstract

To investigate the hormonal, metabolic, and cardiorespiratory effects of xylazine hydrochloride on dairy cows undergoing lateral recumbency and claw trimming. Prospective crossover study. 6 healthy Holstein-Friesian cows. Cows were treated with xylazine (0.05 mg/kg [0.023 mg/lb], IM) or an equal volume of saline (0.9% NaCl) solution 15 minutes before being placed in lateral recumbency for claw trimming. As a third treatment, cows also received xylazine (0.05 mg/kg, IM) but underwent no further manipulation. At preset time intervals, heart rate (HR), respiratory rate (RR), systolic arterial blood pressure, diastolic arterial blood pressure, mean arterial blood pressure (MAP), blood gas values, and plasma concentrations of cortisol, insulin, glucose, lactate, and nonesterified fatty acids (NEFA) were measured, and signs of sedation and ruminal bloat were recorded. Saline solution treatment resulted in a temporary significant increase in SAP, diastolic arterial blood pressure, MAP, RR, and cortisol, lactate, and NEFA concentrations and a significant decrease in arterial oxygen saturation (Sao(2)). Xylazine treatment induced significant decreases in HR, RR, MAP, insulin and NEFA concentrations, and Sao(2) and induced significant in...Continue Reading

References

Apr 1, 1978·Zentralblatt für Veterinärmedizin. Reihe A·M A Aziz, S S Carlyle
Dec 1, 1990·Journal of Veterinary Pharmacology and Therapeutics·J C BrearleyR S Jones
Mar 1, 1987·Journal of Veterinary Pharmacology and Therapeutics·Y Ruckebusch, C Allal
Dec 1, 1988·Journal of Veterinary Pharmacology and Therapeutics·S A Greene, J C Thurmon
Feb 1, 1994·The Journal of Veterinary Medical Science·M TagawaE P Steffey
Nov 26, 1999·The Veterinary Clinics of North America. Food Animal Practice·P D Constable
Feb 13, 2003·Journal of Applied Animal Welfare Science : JAAWS·Francisco Galindo, Donald M Broom
Nov 14, 2006·The Veterinary Record·J N Huxley, H R Whay
Feb 6, 2007·The Veterinary Record·R Eddie CluttonPolly Taylor
May 22, 2007·The Veterinary Record·R Eddie CluttonPolly Taylor
Aug 28, 2007·Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine·H MeyerJ Rehage
Aug 4, 2009·Research in Veterinary Science·G StilwellD M Broom

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Citations

Dec 1, 1991·Journal of Adolescence·P Hazell
Sep 4, 2019·Journal of Dairy Science·Thomas EdeDaniel M Weary
Jan 1, 2014·Journal of Veterinary Medicine·Ukwueze Celestine OkwudiliOna Jonas Anayo
Sep 2, 2020·Animals : an Open Access Journal From MDPI·Mohammed Babatunde SadiqWan Mastura Shaik Mossadeq
Oct 21, 2020·Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere·Maria HeinrichAlexander Starke

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