Effects of Yiqi Huayu Recipe on neural cell adhesion molecule in rats with lumbar nerve root compression

Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine
Chong-Jian ZhouQi Shi

Abstract

To study the effects of Yiqi Huayu Recipe on neural cell adhesion molecule (N-CAM) in neuromuscular junctions during nerve regeneration in rats with lumbar nerve root compression. The rats with lumbar nerve root compression were given Yiqi Huayu Recipe for 10, 20 and 30 days respectively. The distribution of N-CAM in neuromuscular junctions of soleus muscle in rats was examined with immunohistochemical method and confocal laser scanning microscopy technique. The acetylcholine receptor (AChR) was visualized with fluorescein-conjugated alpha-bungarotoxin (alpha-BTX). The overlap areas of N-CAM and AChR sites were measured with NIH image technique. The aggregates, sprouts and extensions of N-CAM in the neuromuscular junctions and the overlap areas of N-CAM and AChR sites in the Yiqi Huayu Recipe-treated group were all better improved than those in the untreated group. The expression of N-CAM is regulated according to the state of innervation for muscles. Yiqi Huayu Recipe may accelerate this nerve regeneration process.

References

Jan 21, 2000·Brain Research. Molecular Brain Research·C S RicardM R Hernandez
Oct 9, 2002·Trends in Biochemical Sciences·Changan Jiang, Erin M Schuman
Sep 2, 2004·Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine·Chong-Jian ZhouMei Liu
Sep 2, 2004·Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine·Qi Shi, Yong-Jun Wang
Sep 24, 2004·Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine·Chong-Jian ZhouQi Shi

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Citations

Mar 7, 2014·Journal of Pediatric Endocrinology & Metabolism : JPEM·Saroj Kumar PatnaikPawan Dhull

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