Effects of Zinc Oxide Nanoparticles on Growth, Intestinal Barrier, Oxidative Status and Mineral Deposition in 21-Day-Old Broiler Chicks.

Biological Trace Element Research
Jiaqi ZhangChao Wang

Abstract

This experiment was to study the effects of zinc oxide nanoparticles (ZnO-NPs) on growth, intestinal barrier, oxidative status, and mineral deposition. In total, 256 one-day-old chicks were randomly allotted to 4 dietary groups and fed with basal diet plus 80 mg/kg ZnSO4 (ZnSO4 group) or plus 40, 80, and 160 mg/kg ZnO-NPs, respectively, for 21 days. Compared with the ZnSO4 group, dietary 40, 80, and 160 mg/kg ZnO-NPs did not alter growth (average daily gain, body weight, and gain to feed ratio), and serum activities of glutamic-pyruvic transaminase, alkaline phosphatase and glutamic oxalacetic transaminase (P > 0.05). However, dietary 80 and 160 mg/kg ZnO-NPs linearly decreased serum D-lactate content and diamine oxidase activity (P < 0.01). Moreover, 80 mg/kg ZnO-NPs enhanced zonula occludens-1 (ZO-1) mRNA expression in jejunal mucosa (P = 0.02). Dietary ZnO-NPs increased total antioxidant capacity activity (P = 0.01), and 80 mg/kg ZnO-NPs decreased malondialdehyde content in jejunal mucosa as compared to the ZnSO4 group (P = 0.02). In contrast, dietary ZnO-NPs did not alter mRNA expressions of superoxide dismutase, catalase, glutathione peroxidase, glutathione S-transferase, heme oxygennase-1 (HO-1) and NAD (P)H: quinone oxid...Continue Reading

References

Apr 1, 1967·The Journal of Nutrition·D R Van Campen, P U Scaife
May 1, 1993·The Journal of Surgical Research·M J MurrayC F Cobb
Jan 7, 1998·Journal of Animal Science·M SandovalR C Littell
Feb 16, 2002·Methods : a Companion to Methods in Enzymology·K J Livak, T D Schmittgen
Mar 15, 2005·American Journal of Clinical Pathology·Monte S WillisSteven H Kroft
Sep 24, 2008·Poultry Science·M Yegani, D R Korver
Feb 3, 2009·The Journal of Biological Chemistry·Truyen NguyenCecil B Pickett
Feb 24, 2009·British Poultry Science·M Choct
Mar 23, 2011·Nanotoxicology·Marie-Noële CroteauEugenia Valsami-Jones
Jul 12, 2012·Cellular and Molecular Life Sciences : CMLS·Takuya Suzuki
Feb 23, 2013·Journal of Photochemistry and Photobiology. B, Biology·Nasrin TalebianMonir Doudi
Jun 15, 2013·Oxidative Medicine and Cellular Longevity·Sang Mi ShinSung Hwan Ki
Jun 30, 2014·Biological Trace Element Research·Cui-Yan ZhaoZhao-Xin Tang
Dec 2, 2014·TheScientificWorldJournal·Sidra SabirSunbal Khalil Chaudhari
May 18, 2016·The Journal of Immunology : Official Journal of the American Association of Immunologists·Thessicar E AntoineDeepak Shukla
Jul 2, 2016·BioMed Research International·Myrlene Carine B TossouYulong Yin
Jan 26, 2017·Biological Trace Element Research·Chao WangTian Wang
Sep 1, 2016·Animal Nutrition·Partha S SwainSellappan Selvaraju
Jan 1, 2015·Nano-micro Letters·Amna SirelkhatimDasmawati Mohamad
Mar 20, 2019·Frontiers in Veterinary Science·Birendra Mishra, Rajesh Jha
May 18, 2020·Poultry Science·Annatachja De GrandeRichard Ducatelle

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