PMID: 8943829Oct 1, 1996Paper

Effects on symptoms and lung function in humans experimentally exposed to diesel exhaust

Occupational and Environmental Medicine
B RudellT Sandström

Abstract

Diesel exhaust is a common air pollutant made up of several gases, hydrocarbons, and particles. An experimental study was carried out which was designed to evaluate if a particle trap on the tail pipe of an idling diesel engine would reduce effects on symptoms and lung function caused by the diesel exhaust, compared with exposure to unfiltered exhaust. Twelve healthy non-smoking volunteers (aged 20-37) were investigated in an exposure chamber for one hour during light work on a bicycle ergometer at 75 W. Each subject underwent three separate double blind exposures in a randomised sequence: to air and to diesel exhaust with the particle trap at the tail pipe and to unfiltered diesel exhaust. Symptoms were recorded according to the Borg scale before, every 10 minutes during, and 30 minutes after the exposure. Lung function was measured with a computerised whole body plethysmograph. The ceramic wall flow particle trap reduced the number of particles by 46%, whereas other compounds were relatively constant. It was shown that the most prominent symptoms during exposure to diesel exhaust were irritation of the eyes and nose and an unpleasant smell increasing during exposure. Both airway resistance (R(aw)) and specific airway resistan...Continue Reading

Associated Clinical Trials

Oct 3, 2012·Christopher Carlsten
Sep 10, 2014·Christopher Carlsten

References

Jan 1, 1992·International Archives of Occupational and Environmental Health·P T Scheepers, R P Bos
Jan 1, 1990·American Journal of Industrial Medicine·U Ulfvarson, R Alexandersson
Jan 1, 1991·American Journal of Industrial Medicine·U UlfvarsonB Bergström
Dec 1, 1987·Scandinavian Journal of Work, Environment & Health·U UlfvarsonM Sorsa
Nov 1, 1986·AJR. American Journal of Roentgenology·J H BairM L Manco-Johnson
Jan 1, 1983·American Journal of Industrial Medicine·J GambleJ Hudak
Jan 1, 1982·Medicine and Science in Sports and Exercise·G A Borg
Jan 1, 1982·The Annals of Occupational Hygiene·R RegerJ Merchant
Jan 1, 1982·The Annals of Occupational Hygiene·M D AttfieldR W Wheeler
Jan 1, 1994·International Archives of Occupational and Environmental Health·B RudellN Stjernberg

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Citations

Jul 6, 2001·American Journal of Industrial Medicine·L C OliverR R Gaita
Feb 4, 2003·Current Allergy and Asthma Reports·David Diaz-SanchezRiccardo Polosa
Dec 7, 2007·The New England Journal of Medicine·James McCreanorJunfeng Zhang
Mar 29, 2000·Archives of Environmental Health·K H Kilburn
Jan 12, 2012·Current Opinion in Pulmonary Medicine·Andrew J GhioMichael C Madden
Feb 27, 2004·Occupational and Environmental Medicine·M L BurrK L Williams
Nov 29, 2008·Occupational and Environmental Medicine·J E HartE Garshick
Aug 18, 1999·Occupational and Environmental Medicine·B RudellT Sandström
Jul 21, 2000·American Journal of Respiratory and Critical Care Medicine·J A NightingaleA Newman-Taylor
Apr 29, 2011·Environmental Health Perspectives·Jacob D McDonaldJoe L Mauderly
Sep 4, 2004·Environmental Health Perspectives·Jacob D McDonaldJoe L Mauderly
Jul 13, 2006·Environmental Health Perspectives·Jaime E HartEric Garshick
Mar 14, 2014·Environmental Health : a Global Access Science Source·Ala MualaThomas Sandström
Jun 19, 2004·Inhalation Toxicology·M D ReedJ L Mauderly
Feb 8, 2005·The Journal of Allergy and Clinical Immunology·Marc Riedl, David Diaz-Sanchez
Jan 1, 2015·International Journal of Coal Science & Technology·Yi ZhengJerry C Tien
Jun 16, 2015·Journal of Environmental and Public Health·Caroline Barakat-HaddadRania Dghaim
Jan 2, 2007·Respiratory Medicine·Jenny BossonAnders Blomberg
Nov 2, 2014·Occupational and Environmental Medicine·Bente UlvestadDag G Ellingsen
Jul 3, 2016·The Science of the Total Environment·Caitlin L MaikawaKrystal J Godri Pollitt
Aug 19, 2016·Journal of Environmental Management·Marc BascomptaJosep Oliva
Feb 26, 2000·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A Blomberg
Sep 7, 2004·Current Opinion in Allergy and Clinical Immunology·Joachim Heinrich, Heinz-Erich Wichmann
Mar 26, 2013·Journal of the American Heart Association·Jeremy P LangrishNicholas L Mills
Jan 14, 2011·Epidemiology·Moniek ZuurbierBert Brunekreef
Nov 14, 2006·American Journal of Industrial Medicine·L Christine Oliver, Heidi Miracle-McMahill
Sep 20, 2007·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·B OftedalP Nafstad
Nov 5, 2008·International Journal of Occupational Medicine and Environmental Health·Nasser M Al-Daghri
Jan 10, 2006·American Journal of Physiology. Lung Cellular and Molecular Physiology·Jonathan CiencewickiIlona Jaspers
May 25, 2011·Inhalation Toxicology·Yehia Y Hammad, Luis F Pieretti
Sep 25, 2012·Journal of Occupational and Environmental Medicine·Sabiha HussainHoward Kipen
Oct 17, 2019·Reviews on Environmental Health·Somayeh Rahimi MoghadamAli Ganjali
Sep 12, 2017·International Journal of Coal Science & Technology·Yi ZhengJerry C Tien
Jul 3, 2020·Archives of Environmental & Occupational Health·Leslie Elliott, Dana Loomis
May 10, 2002·Annals of the New York Academy of Sciences·N Fiedler, H M Kipen

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