PMID: 9183697Jun 9, 1997Paper

Efferent connections of the internal globus pallidus in the squirrel monkey: I. Topography and synaptic organization of the pallidothalamic projection

The Journal of Comparative Neurology
M SidibéY Smith

Abstract

The objectives of this study were, on one hand, to better understand how the segregated functional pathways from the cerebral cortex through the striatopallidal complex emerged in the projections to the thalamus and, on the other hand, to compare the ultrastructure and synaptic organization of the pallidal efferents to the ventrolateral (VL) and centromedian (CM) thalamic nuclei in primates. These aims were achieved by injections of the retrograde-anterograde tracer, biotinylated dextran amine (BDA), in different functional regions of the internal pallidum (GPi) in squirrel monkeys. The location of retrogradely labelled cells in the striatum was determined to ascertain the functional specificity of the injection sites. Injections in the ventrolateral two-thirds of the GPi (group 1) led to retrograde labelling in the postcommissural region of the putamen ("sensorimotor striatum") and plexuses of labelled fibers in the rostral one-third of the principal ventrolateral nucleus (VLp) and the central part of the CM. On the other hand, injections in the dorsal one-third (group 3) and the rostromedial pole (group 4) of the GPi led to retrogradely labelled cells in the body of the caudate nucleus ("associative striatum") and the ventral...Continue Reading

Citations

Sep 5, 2008·Journal of Neurophysiology·Matthew D Johnson, Cameron C McIntyre
Oct 9, 2009·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Suzanne N Haber, Brian Knutson
Apr 1, 2010·Theoretical Biology & Medical Modelling·Byoung-Kyong Min
Dec 24, 2010·Journal of Neurophysiology·Harrison C WalkerErwin B Montgomery
Mar 31, 2016·Brain Structure & Function·Lara Eid, Martin Parent

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