Efficacy and comparison of 0.5% levobupivacaine with 0.75% ropivacaine for peribulbar anaesthesia in cataract surgery

European Journal of Anaesthesiology
A Di DonatoD Celleno

Abstract

The low cardiovascular and neurological toxicity of levobupivacaine has led to its application as a local anaesthetic in a wide variety of specialist applications including peribulbar block for cataract surgery. The aim of this study was to evaluate the efficacy of levobupivacaine 0.5% and to compare block quality vs. ropivacaine 0.75% in peribulbar anaesthesia. We examined 208 patients subjected to cataract surgery by phacoemulsification who were randomized into two groups according to the anaesthetic used for peribulbar block, namely levobupivacaine 0.5% or ropivacaine 0.75%, both with the addition of hyaluronidase. Nerve block was carried out by injection of 6 mL of the anaesthetic mixture equally distributed between the inferotemporal and superonasal areas. The success of the block was evaluated by determining the time of motor and sensory onset, akinesia score, times of motor and sensory offset and satisfaction of the patient and surgeon after 24 h. Pre-block, post-block and postoperative intraocular pressure as well as the duration of surgical intervention was also determined. With respect to ropivacaine, levobupivacaine showed a significant reduction (P < 0.001) in the average motor and sensory onset. Both the akinesia s...Continue Reading

References

Jul 1, 1995·British Journal of Anaesthesia·A P Rubin
Nov 1, 1994·Anaesthesia·A K BrahmaL H Morgan
Jun 1, 1997·British Journal of Anaesthesia·G A DempseyI J Kirby
Apr 22, 1999·British Journal of Anaesthesia·G LyonsR V Johnson
Mar 31, 2000·British Journal of Anaesthesia·G NicholsonG M Hall
Jan 23, 2003·British Journal of Anaesthesia·J I Gómez-ArnauA Arias

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Citations

Jan 5, 2007·European Journal of Anaesthesiology·A Di DonatoA Caricati
Dec 31, 2010·Saudi Journal of Anaesthesia·W RiadN Ahmed
Nov 20, 2013·Journal of Anaesthesiology, Clinical Pharmacology·Sukhminder Jit Singh Bajwa, Jasleen Kaur
Dec 21, 2016·Middle East African Journal of Ophthalmology·Saeed Al-MotowaAbdul Zahoor
Jul 15, 2016·Brazilian Journal of Biology = Revista Brasleira De Biologia·C Moreira-de-SousaC S Fontanetti
May 15, 2010·Current Eye Research·Ludmyla KachkoMoshe Snir
Feb 9, 2020·Clinical Pharmacokinetics·Chantal A A HeppolettePeter M Odor

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