Efficacy and safety of a new formulation kit (shampoo + lotion) containing anti-inflammatory and antioxidant agents to treat hair loss.

Dermatologic Therapy
Alessandra AnzaiMaurízio Mercuri

Abstract

Androgenetic alopecia (AGA) and telogen effluvium (TE) are common causes of hair loss, with limited options for treatment. The aim of this study was to determine the efficacy and safety of a new formulation kit (Pielus Anti-hair loss lotion and shampoo) containing anti-inflammatory and antioxidant agents in patients with TE and/or AGA. This was a prospective, single-arm, open-label study with 35 women and 10 men, median age of 44 years, with clinical diagnosis of TE and/or AGA. They used the combination of shampoo and lotion daily for 90 days. There was nonoccurrence of adverse events. Phototricogram showed increase in the average number of anagen hairs at T90 (P < .001). Scalp microphotography showed increase in total follicular units, total of hairs, and median hair per follicle unit at T90. There was an increase in diameter (P = .003) and in median maximum load and resistance to traction in T90 (P = .040). Combing and washing test demonstrated a decrease in the number of shed hairs before washing (P = .005), after washing (P = .01) and in total (P < .001). The use of shampoo+ lotion daily was safe and effective to attenuate hair loss in men and women with TE and/or AGA.

References

Nov 1, 1996·Archives of Dermatology·F CamachoM J García-Hernández
Dec 21, 1996·BMJ : British Medical Journal·J G Mosley, A C Gibbs
Sep 6, 2000·International Journal of Dermatology·Y F MahéB A Bernard
Sep 6, 2002·Experimental Gerontology·Ralph M Trüeb
Oct 26, 2002·Journal of the American Academy of Dermatology·Elise A OlsenUNKNOWN Dermatologic Consortium for Women's Health
Apr 4, 2003·Dermatology : International Journal for Clinical and Investigative Dermatology·Ralph M Trüeb
Dec 6, 2003·Dermatology : International Journal for Clinical and Investigative Dermatology·Ralph M Trüeb
Dec 17, 2003·The British Journal of Dermatology·G SeveriG G Giles
Oct 1, 2011·Toxicology and Industrial Health·Kyoung Ah KangJin Won Hyun
Dec 2, 2014·Naunyn-Schmiedeberg's Archives of Pharmacology·Seung Hyun ShinJung Chul Kim
Apr 12, 2017·Journal of the American Academy of Dermatology·Areej Adil, Marshall Godwin
Jul 12, 2017·Archives of Dermatological Research·Anna Herman, Andrzej P Herman
Oct 11, 2017·Journal of Dermatological Science·Jungyoon OhnKyu Han Kim
Jun 7, 2018·International Journal of Women's Dermatology·D S Davis, V D Callender
Nov 6, 2018·American Journal of Clinical Dermatology·Dustin H MarksMaryanne M Senna
Feb 21, 2019·International Journal of Trichology·Ralph M TrüebJim R Schwartz

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Giornale Italiano Di Dermatologia E Venereologia : Organo Ufficiale, Società Italiana Di Dermatologia E Sifilografia
Carolina BussolettiLeonardo Celleno
Dermatology : International Journal for Clinical and Investigative Dermatology
Alfredo Rebora
© 2021 Meta ULC. All rights reserved