Efficacy and safety of a partially covered duodenal stent for malignant gastroduodenal obstruction: a pilot study

Gastrointestinal Endoscopy
Dongwook OhM Kim

Abstract

Duodenal stent placement has emerged as an effective and safe palliative treatment for patients with malignant gastroduodenal obstruction. An uncovered enteral stent, however, is susceptible to repeat stenosis because of tumor ingrowth. Although covering an enteral stent with a membrane prevents tumor ingrowth, stent migration continues to be a major unresolved problem. Partially covered metal stents may avoid both tumor ingrowth and stent migration. To evaluate the clinical and technical efficacy and the safety of a partially covered duodenal stent for malignant gastroduodenal obstruction. Retrospective, observational study. Tertiary-care medical center. Twenty patients with malignant gastroduodenal obstruction received palliative treatment with partially covered duodenal stents. Endoscopic stent placement. Technical success, clinical success, patency, and adverse events. Stent placement was successful in all 20 patients (technical success rate, 100%), and symptoms improved in 19 (clinical success rate, 95%). The Gastric Outlet Obstruction Scoring System score improved significantly (P < .001). Eight patients (40%) developed tumor overgrowth, whereas none showed stent migration. Median stent patency was 79.5 days (range 13-198...Continue Reading

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Citations

Mar 20, 2016·Current Treatment Options in Gastroenterology·Emanuele Dabizzi, Paolo Giorgio Arcidiacono
Feb 1, 2017·The American Journal of Gastroenterology·Evan L FogelStuart Sherman
Mar 6, 2019·JGH Open : an Open Access Journal of Gastroenterology and Hepatology·Vinay KumarVivek A Saraswat
Jul 9, 2016·Current Opinion in Gastroenterology·Yen-I Chen, Mouen A Khashab
Feb 23, 2020·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Jordan OrrPatrick Yachimski

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