PMID: 8607688Apr 1, 1996Paper

Efficacy and safety of a percutaneous right ventricular assist system

The Annals of Thoracic Surgery
M YanoY Koga

Abstract

Mechanical right ventricular assistance is necessary in the management of profound right ventricular failure resistant to medical therapy. Conventional right ventricular assistance requires a thoracotomy. We developed a technique for assisting the failing right ventricle without thoracotomy. We implanted the percutaneous right ventricular assist system in animals to test its feasibility and safety. A feasibility study was performed in a right ventricular failure model using 12 open chest dogs, and we examined the effects of the system hemodynamically. Next, the system was implanted into 6 goats and driven for 2 to 8 days. Institution of the percutaneous right ventricular assist system revealed overall hemodynamic improvement on right ventricular failure in dogs. In the goat experiment, no animal died from cannula-related complications. No damage to the intracardiac structures and no pulmonary edema were seen. Plasma free hemoglobin concentration did not exceed 10 mg/dL. The percutaneous right ventricular assist system is safe and effective in the management of right ventricular failure.

References

Jan 1, 1977·Transactions - American Society for Artificial Internal Organs·J L PetersW J Kolff
Jan 1, 1989·The Annals of Thoracic Surgery·S J PhillipsL A Iannone
Jan 1, 1989·The Annals of Thoracic Surgery·R M BolmanJ Saffitz
Jul 1, 1988·The Journal of Surgical Research·B ToporoffJ N Cunningham
Feb 1, 1985·World Journal of Surgery·D J FarrarJ D Hill

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Citations

Aug 3, 2006·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Ho Sung SonHyoung Mook Kim
Mar 20, 2001·Journal of Cardiothoracic and Vascular Anesthesia·M J Griffin, R L Hines

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