Efficacy and Safety of Bioabsorbable Bone Hemostatic Agent in Total Knee Arthroplasty: A Prospective Randomized Controlled Trial.

Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Jong-Keun KimHyuk-Soo Han

Abstract

Although a bioabsorbable bone hemostatic agent (BBHA) was developed approximately 20 years ago to overcome the shortcomings of conventional bone wax, its bleeding control capacity has not yet been studied. This study was aimed at investigating the efficacy and safety of BBHA in total knee arthroplasty (TKA). Sixty-two patients who underwent unilateral primary TKA for knee osteoarthritis were included and randomized to the control or BBHA group. Before releasing the tourniquet, BBHA was applied on the bone-cut surface that was not covered by implants. The primary variable was the drainage volume during the postoperative period. The secondary outcomes were total estimated blood loss (EBL), hemoglobin level, hematocrit level, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) level, range of motion (ROM), pain visual analog scale (VAS) score, and rate of complications. There were no significant differences in drainage volume or EBL between the 2 groups. Hemoglobin and hematocrit levels were higher in the BBHA group during the 4-week postoperative period; however, the intergroup differences were not significant. The ESR, CRP, ROM, and pain VAS scores in the BBHA group were not significantly different from the correspond...Continue Reading

References

Aug 1, 1996·Clinical Orthopaedics and Related Research·E D ArringtonN A Davino
Jul 1, 1997·Journal of Pharmaceutical Sciences·R C JewellW A Wargin
Feb 13, 2004·The Journal of Bone and Joint Surgery. American Volume·Lih-Yuann ShihHsin-Nung Shih
Jun 29, 2004·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Claudio SchonauerAldo Moraci
Jun 14, 2006·The Journal of Craniofacial Surgery·Tadeusz WelliszTimothy C Fisher
Jan 16, 2008·Clinical Orthopaedics and Related Research·Tadeusz WelliszJonathan K Armstrong
Dec 2, 2009·The Journal of the American Academy of Orthopaedic Surgeons·R Justin Thoms, Scott E Marwin
Dec 17, 2009·Annals of Surgery·Hardean E AchneckJeffrey H Lawson
Jun 1, 2011·Pediatrics·Amy L BaxterMatthew M Wyatt
May 17, 2012·Journal of Orthopaedics and Traumatology : Official Journal of the Italian Society of Orthopaedics and Traumatology·Luigi SabatiniRoberto Scagnelli
May 25, 2012·The Journal of Bone and Joint Surgery. American Volume·Zhi-Gao YangLi-Dong Wu
Jul 5, 2012·Clinical Orthopaedics and Related Research·Lucian B SolomonMartin Beck
Oct 15, 2013·The Annals of Thoracic Surgery·Rikke F VestergaardJohn M Hasenkam
Feb 14, 2014·Archives of Orthopaedic and Trauma Surgery·Jerry Yongqiang ChenSeng Jin Yeo
Jan 17, 2017·The Journal of Arthroplasty·Ing H MooKein B Poon
Oct 19, 2019·The Journal of Trauma and Acute Care Surgery·Allison J TompeckMayur Narayan

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Related Papers

The Journal of Craniofacial Surgery
Vivekanand S KattimaniLingamaneni Krishna Prasad
Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Elnaz PashaeiNizamettin Aydin
Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre
Maribel Herrera-RuizJaime Tortoriello
© 2021 Meta ULC. All rights reserved