Efficacy and safety of endoscopic submucosal tunnel dissection for superficial esophageal squamous cell carcinoma and precancerous lesions

World Journal of Gastroenterology : WJG
Jin WangJin-Lin Yang

Abstract

To evaluate the clinical outcomes of patients who underwent endoscopic submucosal tunnel dissection (ESTD) for esophageal squamous cell carcinoma (ESCC) and precancerous lesions. ESTD was performed in 289 patients. The clinical outcomes of the patients and pathological features of the lesions were retrospectively reviewed. A total of 311 lesions were included in the analysis. The en bloc rate, complete resection rate, and curative resection rate were 99.04%, 81.28%, and 78.46%, respectively. The ESTD procedure time was 102.4 ± 35.1 min, the mean hospitalization time was 10.3 ± 2.8 d, and the average expenditure was 3766.5 ± 846.5 dollars. The intraoperative bleeding rate was 6.43%, the postoperative bleeding rate was 1.61%, the perforation rate was 1.93%, and the postoperative infection rate was 9.65%. Esophageal stricture and positive margin were severe adverse events, with an incidence rate of 14.79% and 15.76%, respectively. No tumor recurrence occurred during the follow-up period. ESTD for ESCC and precancerous lesions is feasible and relatively safe, but for large mucosal lesions, the rate of esophageal stricture and positive margin is high.

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Citations

May 13, 2020·Expert Review of Gastroenterology & Hepatology·Yuyong TanDeliang Liu
Feb 28, 2019·World Journal of Gastroenterology : WJG·Ning-Li ChaiYa-Qi Zhai
Jul 1, 2021·Arquivos De Gastroenterologia·Tarso Magno Leite RibeiroRoberto Gardone Guimarães

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Methods Mentioned

BETA
dissection
biopsies
biopsy

Software Mentioned

SPSS

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