Efficacy and Safety of Ledipasvir/Sofosbuvir for the Treatment of Chronic Hepatitis C in Persons With Sickle Cell Disease

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Juhi MoonMark S Sulkowski

Abstract

Patients with sickle cell disease are at high risk for chronic hepatitis C infection. Prior treatment has been limited due to the use of ribavirin causing hemolytic anemia and interferon causing cytopenias. We demonstrate the safety and efficacy of fixed-dose combination ledipasvir and sofosbuvir for 12 weeks in this population.

References

Oct 3, 2002·Gastroenterology·John G McHutchisonUNKNOWN International Hepatitis Interventional Therapy Group
Nov 3, 2009·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Ashwani K SingalGagan K Sood
Dec 2, 2009·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Amit G SingalPhilip S Schoenfeld
Apr 12, 2014·The New England Journal of Medicine·Kris V KowdleyUNKNOWN ION-3 Investigators
Apr 15, 2014·The New England Journal of Medicine·Nezam AfdhalUNKNOWN ION-2 Investigators
Apr 15, 2014·The New England Journal of Medicine·Nezam AfdhalUNKNOWN ION-1 Investigators
Jun 26, 2015·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·UNKNOWN AASLD/IDSA HCV Guidance Panel

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Citations

May 23, 2019·Clinical Pharmacokinetics·Elise J SmoldersDavid M Burger
Nov 10, 2018·The American Journal of Gastroenterology·Harrys A TorresBruno P Granwehr
Mar 3, 2020·Frontiers in Molecular Biosciences·Laura MaffeiStefano Materazzi
Dec 7, 2019·Hematology·Abid R Suddle
Sep 22, 2020·Journal of Hepatology·UNKNOWN European Association for the Study of the Liver. Electronic address: easloffice@easloffice.euUNKNOWN Panel members:

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