Efficacy and safety of picosecond 755-nm alexandrite laser with diffractive lens array for non-ablative rejuvenation in Chinese skin

Lasers in Surgery and Medicine
Heidi WatHenry Hin-lee Chan

Abstract

The picosecond alexandrite laser with diffractive lens array (DLA) offers the dual advantages of a picosecond pulse duration and the fractionated delivery of laser energy. This study explores the efficacy and safety of the DLA for treatment of multiple aesthetic concerns associated with photoaging of the face including skin texture irregularities, dyspigmentation, enlarged pore size, rhytides, and skin laxity. This prospective, evaluator-blinded trial enrolled Fitzpatrick skin type III-IV patients with mild to moderate signs of facial photoaging. Patients received six full face treatments at 4 week intervals for a total of 107 treatments. Standardized photography was obtained at baseline and at 1, 2, and 3 month follow-up visits. Two independent blinded evaluators rated each of the five signs of photoaging on a 10-point visual analog scale (VAS) at each follow-up visit compared to baseline. A global aesthetic improvement score was also assigned at each follow-up visit. Secondary outcomes included patient-rated pain and heat sensation on a 10-point VAS, and overall satisfaction. Adverse events were noted after each treatment and at each follow-up visit. A total of 18 Chinese patients age 35-59 completed the study. A statisticall...Continue Reading

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Citations

Dec 19, 2018·Lasers in Surgery and Medicine·Kristen M Kelly
Feb 12, 2020·Journal of Cosmetic Dermatology·Joseph N MehrabiOfir Artzi
Apr 14, 2020·Lasers in Surgery and Medicine·Douglas C WuHenry H L Chan
Nov 9, 2020·Lasers in Surgery and Medicine·Weeranut PhothongNutthamon Bowornsathitchai
Feb 6, 2021·Lasers in Surgery and Medicine·Christina S M WongHenry H L Chan
Aug 18, 2021·Lasers in Surgery and Medicine·Arielle N B KauvarKevin Schomacker

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