Efficacy and safety of radiofrequency ablation for lung cancers: A systematic review and meta-analysis

European Journal of Radiology
Gui-Yuan LiSheng-Ming Yi

Abstract

To evaluate the efficacy and safety of radiofrequency ablation(RFA) for patients with lung cancers using meta-analysis. A literature search (PubMed, Embase, Web of science and China National Knowledge Infrastructure) was undertaken until August 2017 to identify sufficient studies evaluating the efficacy and safety of RFA. Pooled proportions of estimates were calculated by performing the random effect model, including technical success rate, recurrence rate, local tumor progression rate and complications. A total of 25 eligible studies were collected, giving a sample size of 1989 patients with 3025 lung tumors. In the present series, the pooled technical success rate was 96%(95%CIs: 93%-100%). Further, we observed pooled recurrence rate of 35%(95%CIs: 12%-59%) following RFA. Additionally, the pooled rate of local tumor progression was 26%(95%CIs: 20%-32%). One hundred and ninety major complications of RFA were reported in 20 studies, giving a pooled proportion of 6% (95%CIs: 3%-8%) for major RFA complications. Pooled rate of minor complications was 27% (95%CIs:14%-41%). In this meta-analysis, RFA was found to be a safe and efficient treatment for the patients with lung cancers. The efficacy and safety of RFA for lung cancer dese...Continue Reading

Citations

Oct 16, 2018·Pain Management·Jonathan E Silverman, Amitabh Gulati
Jul 4, 2020·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Myung Sub KimTae Yoon Oh
Jul 25, 2020·The British Journal of Radiology·Thomas Helmberger
Feb 26, 2020·Cardiovascular and Interventional Radiology·Massimo VenturiniGianpaolo Carrafiello
Jan 16, 2020·Journal of Cancer Research and Therapeutics·Dongdong WangXiaoguang Li
Apr 26, 2019·Thoracic Cancer·Fei CaoWeijun Fan
Jul 10, 2020·Respirology : Official Journal of the Asian Pacific Society of Respirology·Daniel P Steinfort, Felix J F Herth
Dec 30, 2020·Thoracic Cancer·Fanlei KongXiaoguang Li
Apr 23, 2021·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Sheng XuXiao-Guang Li
Apr 30, 2021·Insights Into Imaging·Alfredo Páez-CarpioIvan Vollmer
Jun 1, 2021·Cancer Treatment and Research Communications·Jana S HopstakenKoen J Hartemink
Aug 4, 2021·Deutsche medizinische Wochenschrift·Jörn Henze, David Maintz

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