Efficacy and safety of transepithelial photorefractive keratectomy

Journal of Cataract and Refractive Surgery
Soheil Adib-MoghaddamSamuel Arba Mosquera

Abstract

Transepithelial photorefractive keratectomy (PRK) was introduced to prevent complications from conventional PRK and femtosecond laser-assisted laser in situ keratomileusis (LASIK). In the 2-step platform, phototherapeutic keratectomy is followed by PRK. It did not show notable safety or efficacy superiorities over conventional PRK. In the conventional single-step transepithelial PRK, ablation of epithelium and stroma occurs in a single continuous session by an Amaris laser. It showed better comparative safety results. Reverse single-step transepithelial PRK and the platform using smart-pulse technology were recent improvements in the single-step Amaris laser. They provide a smoother postablative stromal bed counter. In the refined single-step platform, a modified nomogram is used for determination of ablation parameters, along with modifications in postablative measures. It yielded better comparative results in hyperopia. Controlled trials comparing reverse, smart-pulse technology-equipped, or refined platforms of single-step transepithelial PRK with other modern laser-assisted methods could provide more robust evidence on the topic. Some key elements with significant roles in post-transepithelial PRK outcomes are discussed.

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Citations

Nov 25, 2020·Indian Journal of Ophthalmology·Rajesh FoglaPooja Khamar
Nov 27, 2020·European Journal of Ophthalmology·Nimrata Bajaj DhamiGobinder Singh Dhami
Dec 1, 2020·Journal of Cataract and Refractive Surgery·Alexandra SabauBerthold Seitz
May 6, 2021·Journal of Clinical Medicine·José-María Sánchez-GonzálezCarlos Rocha-de-Lossada
Aug 20, 2021·Clinical Ophthalmology·Shereef M AbdelwahabMaha A Elfayoumi
Dec 24, 2021·Indian Journal of Ophthalmology·Abhishek Dave

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