PMID: 6108299Jan 1, 1980Paper

Efficacy and side effects of lorazepam, oxazepam, and temazepam as sleeping aids in psychogeriatric inpatients

International Pharmacopsychiatry
M LinnoilaJ Auvinen

Abstract

The efficacy and side effects of 2 mg of lorazepam, 30 mg of oxazepam, and 20 mg of temazepam as sleeping aids were investigated in 20 psychogeriatric inpatients. The drugs were administered in a random order, double-blind, for 7 night each. All of these short half-life benzodiazepines proved efficacious in maintaining sleep. None of them reduced initial sleep latency. Oxazepam and to a lesser degree temazepam induced withdrawal insomnia during the first night after the treatments. The withdrawal of lorazepam induced a delayed but prolonged insomnia in 3 patients. Both lorazepam and oxazepam had muscle relaxant side effects after awakening.

Citations

Jan 1, 1987·Psychopharmacology·J V Hinrichs, M M Ghoneim
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Apr 1, 1995·Journal of Geriatric Psychiatry and Neurology·J T LittleL Volicer
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Nov 17, 2016·The Cochrane Database of Systematic Reviews·Jenny McCleeryAnn L Sharpley
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Nov 15, 2020·The Cochrane Database of Systematic Reviews·Jenny McCleery, Ann L Sharpley

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