Efficacy of a 3-year course of sublingual immunotherapy for mite-induced allergic rhinitis with a 3-year follow-up.

Immunotherapy
Wen-Bo ChenLei Cheng

Abstract

Aim: To evaluate the long-term efficacy of sublingual immunotherapy (SLIT) in treating mite-sensitized allergic rhinitis (AR). Materials & methods: 150 AR children were randomly divided into SLIT and pharmacotherapy (PT) groups, receiving a 3-year course of SLIT along with PT or PT only. Results: The symptom and medication scores at the 3- and 6-year follow-up were significantly lower compared with the baseline levels in both groups, while the values were significantly lower in SLIT group than in PT group. No significant differences were observed between 3- and 6-year follow-up in SLIT group. Conclusion: 3-year SLIT along with PT appeared more effective compared with PT only for mite-induced AR in children, and the treatment was effective for at least 3 consecutive years even after SLIT ceased.

References

May 15, 2001·Allergy·S Dreborg
Oct 10, 2002·International Archives of Allergy and Immunology·Wayne R ThomasRichard M O'Brien
Feb 1, 2008·The Journal of Allergy and Clinical Immunology·Timothy J CraigUNKNOWN National Heart, Lung, and Blood Institute's Asthma Clinical Research Network
Jan 13, 2009·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·H-J MallingA Didier
Feb 13, 2009·Allergy·J LiUNKNOWN China Alliance of Research on Respiratory Allergic Disease
Feb 17, 2009·The Journal of Allergy and Clinical Immunology·Harold S Nelson
Sep 25, 2010·Allergology International : Official Journal of the Japanese Society of Allergology·Syuji YonekuraYoichi Kohno
Jun 28, 2011·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Ji-Eun LeeDong-Young Kim
Jan 17, 2012·The Journal of Allergy and Clinical Immunology·Moisés A CalderónPascal Demoly
Jul 28, 2013·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Howard C CrispJames M Quinn
Feb 11, 2016·World Journal of Clinical Pediatrics·Dimitri PoddigheGian Luigi Marseglia
Apr 17, 2016·Immunology and Allergy Clinics of North America·David I BernsteinJonathan A Bernstein
Mar 20, 2018·Allergology International : Official Journal of the Japanese Society of Allergology·Xuandao LiuDe Yun Wang
Jun 21, 2018·Allergologia et immunopathologia·L Cheng, W-C Zhou
Jun 28, 2018·Allergy, Asthma & Immunology Research·Lei ChengLuo Zhang
Oct 30, 2018·Allergy·Oliver PfaarLuo Zhang
Feb 8, 2020·Journal of Thoracic Disease·Huabin LiUNKNOWN Chinese Society of Allergy (CSA)

❮ Previous
Next ❯

Citations

Jul 22, 2021·International Journal of General Medicine·Li WangYaping Duan

❮ Previous
Next ❯

Methods Mentioned

BETA
pharmacotherapy
protein assay

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
Zhenghua Huang, Ai Zhou
Otolaryngologic Clinics of North America
Thomas S Edwards, Sarah K Wise
International Journal of Immunopathology and Pharmacology
L TerraccianoE Galli
Current Allergy and Asthma Reports
Carlos E Baena-CagnaniG Passalacqua
© 2021 Meta ULC. All rights reserved