Efficacy of a silver lipidocolloid dressing on heavily colonised wounds: a republished RCT

Journal of Wound Care
I LazarethA Zagnoli

Abstract

Nearly all open wounds are contaminated by microorganisms. This generally corresponds to simple bacterial growth, without leading to deleterious effects or compromising the progress of the healing process. In acute wounds, the probability of wound infection increases as the level of contamination does. However, it is more complex for chronic wounds, which are able to contain and tolerate large amounts of bacteria, many times higher than the usual threshold level (>105 bacteria/g of tissue) defining infection in acute wounds,1 without inducing local signs. Nevertheless, many clinical and experimental studies indicate that the probability for chronic wounds to heal properly is limited when the bacterial load exceeds this level of contamination; even when body defences are still able to prevent tissue invasion, bacteria can impair wound healing.

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Citations

Apr 30, 2013·The Journal of Dermatology·Jean-François BissonLaetitia Thomassin
May 15, 2015·Pain Management Nursing : Official Journal of the American Society of Pain Management Nurses·Yun HuaXiao-Li Chen
Sep 14, 2016·Journal des maladies vasculaires·I Lazareth
Jun 24, 2017·The Cochrane Database of Systematic Reviews·Maggie J WestbyGill Norman
Apr 5, 2016·The Cochrane Database of Systematic Reviews·Gill NormanSaori Goto
Jun 16, 2018·The Cochrane Database of Systematic Reviews·Gill NormanJo C Dumville
Jan 31, 2019·International Wound Journal·Ut T BuiHelen Edwards
Oct 9, 2019·Plastic and Reconstructive Surgery. Global Open·Ibrahim KhansaJeffrey E Janis
Feb 10, 2018·Journal of Wound Care·Steven L Percival

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