Efficacy of a topical formulation of henna (Lawsonia inermis L.) in contact dermatitis in patients using prosthesis: A double-blind randomized placebo-controlled clinical trial

Complementary Therapies in Medicine
Mehdi NiaziMehrzad Mehrbani

Abstract

Contact dermatitis is a common complication in prosthetic limb users. There are no effective, available and cheap treatments for skin problems of these patients. In traditional Iranian medicine, henna (Lawsonia inermis L.) is a plant that has anti-inflammatory, antimicrobial and skin-enhancing properties, all of which are beneficial for people with artificial limbs. The aim of this study was to assess the efficacy of a topical henna preparation in management of contact dermatitis in patients using lower limb prosthetics. The current randomized, double-blind, placebo-controlled clinical trial was conducted on ninety-five participants with lower extremity amputation using limb prosthetics, aged 12-70 years who complained of contact dermatitis. They were randomly assigned to receive either two weeks of topical henna preparation every night as the intervention group, or topical placebo as the control group. Participants were instructed to spread henna preparation on the surfaces of the amputated limb that were in contact with the prosthesis. Severity of contact dermatitis symptoms was set as the primary outcome measure. Edema, papules and erythema were evaluated by a physician using standard color atlas. Secondary outcomes included...Continue Reading

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Citations

Sep 22, 2020·Dose-response : a Publication of International Hormesis Society·Muhammad Amjad ChishtiAbdul Hayee
May 11, 2021·BMC Complementary Medicine and Therapies·Qun ZhangXuedong Zhou
Sep 27, 2021·Journal of Cosmetic Dermatology·Mehdi PasalarMohammad Mahdi Parvizi

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