PMID: 2492354Feb 10, 1989Paper

Efficacy of an attachable subcutaneous cuff for the prevention of intravascular catheter-related infection. A randomized, controlled trial

JAMA : the Journal of the American Medical Association
R H FlowersB M Farr

Abstract

We performed a randomized controlled trial of an attachable subcutaneous cuff for the prevention of central vascular catheter-related infection among patients receiving intensive care. Catheters were placed percutaneously into new sites with or without a cuff and were dressed with polyantibiotic ointment containing polymyxin, neomycin, and bacitracin. Microbial colonization developed in 34.5% of 29 control and 7.7% of 26 cuffed catheters. Catheter-related bloodstream infection occurred with 13.8% of control vs 0% of cuffed catheters. The cuff was not associated with adverse effects. An unexpectedly large proportion (75%) of catheter infections were due to Candida albicans. This may have been due, in part, to the use of polyantibiotic ointment, as suggested by a pooled analysis of previous trials that demonstrated increased Candida colonization of catheters with the ointment, which is not fungicidal. These data suggest that the cuff can reduce the incidence of catheter-related infection among high-risk patients receiving catheter site care with an antibacterial ointment.

Citations

Oct 20, 2004·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Michael Allon
Dec 3, 2014·The Surgical Clinics of North America·Mohamed F Osman, Reza Askari
Apr 5, 2002·Clinical Microbiology Reviews·Rodney M Donlan, J William Costerton
May 22, 2004·Critical Care : the Official Journal of the Critical Care Forum·Stefania CicaliniNicola Petrosillo
Oct 27, 2004·Antimicrobial Agents and Chemotherapy·I FrancoliniP Stoodley
Mar 30, 2006·Antimicrobial Agents and Chemotherapy·John J Curtin, Rodney M Donlan
Apr 28, 2006·Antimicrobial Agents and Chemotherapy·Euan BurtonSrinivasa Madhyastha
Jun 1, 2009·Seminars in Interventional Radiology·Martha-Grace KnuttinenCharles A Owens
Apr 5, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Naomi P O'GradyUNKNOWN Healthcare Infection Control Practices Advisory Committee (HICPAC)
Apr 7, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Naomi P O'GradyUNKNOWN Healthcare Infection Control Practices Advisory Committee (HICPAC) (Appendix 1)
Sep 21, 2004·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Fabio PaglialongaNicola Principi
Nov 30, 2000·Current Infectious Disease Reports·D P Calfee, B M Farr
Apr 19, 2005·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Torben OstendorfHartmut Goldschmidt
Nov 19, 2003·Journal of Palliative Medicine·Gary M Reisfield, George R Wilson
Dec 17, 2004·Anaesthesia·A P Hall, W C Russell
Feb 11, 1993·The New England Journal of Medicine·P J Fabri
Mar 21, 2003·The New England Journal of Medicine·David C McGee, Michael K Gould
Oct 12, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·B M Farr
Apr 10, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Christopher J Crnich, Dennis G Maki
Dec 4, 2002·American Journal of Infection Control·Naomi P O'gradyUNKNOWN Healthcare Infection Control Practices Advisory Committee
Sep 29, 1999·Cardiovascular and Interventional Radiology·J Namyslowski, N H Patel
Dec 2, 2014·Pathogens·Maria José AlvesManuela Pintado
Jul 1, 1990·Mayo Clinic Proceedings·M L CoronaR L Thompson
Mar 14, 2000·Chest·P E Marik
Nov 22, 2011·Techniques in Vascular and Interventional Radiology·Mary E Meek
Jul 27, 2011·The Surgical Clinics of North America·Kristen M RhodaEzra Steiger
Apr 29, 2011·American Journal of Infection Control·Naomi P O'GradyUNKNOWN Healthcare Infection Control Practices Advisory Committee
Feb 15, 2011·Infectious Disease Clinics of North America·David J Weber, William A Rutala
Dec 7, 2010·International Journal of Antimicrobial Agents·E BouzaP Muñoz
Dec 29, 2009·Journal of Vascular and Interventional Radiology : JVIR·Scott O TrerotolaJesse Chittams
Mar 18, 2008·Journal of Controlled Release : Official Journal of the Controlled Release Society·Shunmugaperumal TamilvananAnnick Ludwig
Apr 5, 2001·Journal of Vascular and Interventional Radiology : JVIR·H M RichardD A Van Echo
Nov 29, 2002·Seminars in Roentgenology·Brian Funaki
Nov 20, 2008·Journal of Applied Microbiology·M D P WillcoxN Cole
Mar 21, 2008·Journal of Advanced Nursing·Prabha RamrituNicholas Graves
Mar 22, 2005·Intensive & Critical Care Nursing : the Official Journal of the British Association of Critical Care Nurses·Chris Theaker
Dec 1, 1996·American Journal of Surgery·K M Bullard, D L Dunn
Oct 8, 1992·The New England Journal of Medicine·D K CobbB M Farr

❮ Previous
Next ❯

Related Concepts

Related Feeds

Candidiasis

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Candidiasis (ASM)

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Candida albicans

Candida albicans is an opportunistic, fungal pathogen of humans that frequently causes superficial infections of oral and vaginal mucosal surfaces of debilitated and susceptible individuals. Discover the latest research on Candida albicans here.