Efficacy of Antioxidant Supplementation on Conventional and Advanced Sperm Function Tests in Patients with Idiopathic Male Infertility

Antioxidants
Mohamed ArafaHaitham Elbardisi

Abstract

Antioxidants are used in the empirical treatment of infertile men. The aim of this study was to evaluate the effects of antioxidant therapy on conventional semen parameters and advanced sperm function tests in men seeking fertility treatment. A total of 148 infertile men of unknown etiology were divided into idiopathic (n = 119) and unexplained male infertility (UMI; n = 29). All participants were treated with the antioxidant supplement 'FH PRO for Men' for a period of three months. Compared with pretreatment results, there was a significant improvement in conventional semen parameters including sperm concentration, total and progressive motility and normal morphology, and seminal oxidation reduction potential (ORP), and sperm DNA fragmentation (SDF) in idiopathic infertile men. The changes were more prominent in idiopathic infertile men positive for ORP and SDF. UMI patients showed an improvement in progressive motility, ORP, and SDF after antioxidant treatment. Statistical analysis revealed that the efficacy of FH PRO for Men was significant in idiopathic male infertility compared with UMI. Treatment of idiopathic male infertility patients with the FH PRO for Men antioxidant regimen for three months resulted in a significant ...Continue Reading

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Citations

Jul 22, 2020·Andrologia·Ralf HenkelDavid Fisher
Jul 10, 2020·Antioxidants·Taylor PiniMandy G Katz-Jaffe
Jan 26, 2021·Reproductive Medicine and Biology·Teppei TakeshimaYasushi Yumura
Mar 5, 2021·The World Journal of Men's Health·Ashok AgarwalRalf Henkel
Jun 3, 2021·Antioxidants·Gianmaria SalvioGiancarlo Balercia
Aug 28, 2021·Antioxidants·Maria Nunzia De LucaVittorio Unfer

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Clinical Trials Mentioned

NCT03464656

Software Mentioned

MedCalc

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