Efficacy of bisacodyl given as part of a polyethylene glycol-based bowel preparation prior to colonoscopy in hospitalized patients: a prospective ramdomized trial

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
Ki Bae BangDong Il Park

Abstract

Inpatient status can cause inadequate bowel preparation. The majority of previous studies regarding bowel preparation have focused on comparing the effects of different purgative regimens in outpatients. However, data on bowel preparation for inpatients are lacking. The aim of this study was to investigate whether bisacodyl plus polyethylene glycol (PEG) can improve bowel preparation in hospitalized patients. A prospective, randomized and observer-blind study was performed. A total of 196 hospitalized patients undergoing colonoscopy were randomized to receive 4 L PEG (PEG only group) or 4 L PEG+bisacodyl 10 mg (bisacodyl added group). The adequacy of bowel preparation was scored using the Ottawa bowel preparation scale. One hundred and eighty-three subjects completed the study; 96 in the bisacodyl added group and 87 in the PEG only group. There were no significant differences between the bisacodyl added group and the PEG only group with respect to the score of bowel cleansing (3.59±B1;2.81 vs. 3.82±B1;3.03, p=0.607), quality of bowel cleansing (adequate preparation 89.6% vs. 85.1%, p=0.380), and overall adverse events (66.7% vs. 52.9%, p=0.057). However, a larger proportion of patients in the PEG only group were able to ingest ...Continue Reading

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Citations

Feb 4, 2016·Arquivos De Gastroenterologia·Seyed Mohsen DehghaniSaeed Ghanbari
Aug 25, 2016·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Jae Ho SeongHyun Soo Kim
Nov 6, 2018·Current Treatment Options in Gastroenterology·Myriam MartelAlan N Barkun
Oct 22, 2019·JGH Open : an Open Access Journal of Gastroenterology and Hepatology·Dileep MangiraGregor Brown

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